P8104
Anti-Phospholipase Cγ1 antibody produced in rabbit
affinity isolated antibody, buffered aqueous solution
Synonym(s):
Anti-PLCγ1
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About This Item
UNSPSC Code:
12352203
MDL number:
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 148 kDa
species reactivity
mouse, human
technique(s)
immunoprecipitation (IP): 5 μg using NIH3T3 mouse fibroblasts cell lysate, microarray: suitable, western blot: 1:5,000 using whole cell extract of human Jurkat cells
shipped in
dry ice
storage temp.
−20°C
Gene Information
human ... PLCG1(5335)
mouse ... Plcg1(18803)
rat ... Plcg1(25738)
Immunogen
synthetic peptide corresponding to the C-terminal region of bovine PLCγ1 (amino acids 1246-1262). This sequence is identical in rat PLCγ1 and highly conserved (single amino acid substitution) in human PLCγ1.
Physical form
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 15 mM sodium azide
Regulatory Information
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Katy L Everett et al.
The Journal of biological chemistry, 284(34), 23083-23093 (2009-06-18)
Phospholipase C gamma isozymes (PLC gamma 1 and PLC gamma 2) have a crucial role in the regulation of a variety of cellular functions. Both enzymes have also been implicated in signaling events underlying aberrant cellular responses. Using N-ethyl-N-nitrosourea (ENU)
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