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Merck
CN

P8104

Sigma-Aldrich

Anti-Phospholipase Cγ1 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

Synonym(s):

Anti-PLCγ1

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About This Item

MDL number:
UNSPSC Code:
12352203
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biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 148 kDa

species reactivity

mouse, human

technique(s)

immunoprecipitation (IP): 5 μg using NIH3T3 mouse fibroblasts cell lysate
microarray: suitable
western blot: 1:5,000 using whole cell extract of human Jurkat cells

shipped in

dry ice

storage temp.

−20°C

Gene Information

human ... PLCG1(5335)
mouse ... Plcg1(18803)
rat ... Plcg1(25738)

Immunogen

synthetic peptide corresponding to the C-terminal region of bovine PLCγ1 (amino acids 1246-1262). This sequence is identical in rat PLCγ1 and highly conserved (single amino acid substitution) in human PLCγ1.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 15 mM sodium azide

Regulatory Information

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Katy L Everett et al.
The Journal of biological chemistry, 284(34), 23083-23093 (2009-06-18)
Phospholipase C gamma isozymes (PLC gamma 1 and PLC gamma 2) have a crucial role in the regulation of a variety of cellular functions. Both enzymes have also been implicated in signaling events underlying aberrant cellular responses. Using N-ethyl-N-nitrosourea (ENU)

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