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Merck
CN

P8607

Sigma-Aldrich

Anti-Potassium Channel Kv1.1 antibody produced in rabbit

affinity isolated antibody, lyophilized powder

Synonym(s):

Anti-Dendrotoxin-Sensitive Delayed Rectifier, Anti-MBK1, Anti-MK1

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About This Item

MDL number:
UNSPSC Code:
12352203
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biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

clone

polyclonal

form

lyophilized powder

species reactivity

mouse, rat

technique(s)

western blot (chemiluminescent): 1:200

storage temp.

−20°C

Gene Information

mouse ... Kcna1(16485)
rat ... Kcna1(24520)

Immunogen

GST fusion protein from the C-terminal of mouse potassium channel Kv1.1 corresponding to amino acids 416-495.

Biochem/physiol Actions

Recognizes a full-length Kv1.1 protein. Does not cross-react with other potassium channel antigens.

Physical form

Lyophilized at ~0.2 mg/ml from phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 0.025% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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K G Chandy et al.
Science (New York, N.Y.), 247(4945), 973-975 (1990-02-23)
To understand the molecular mechanisms responsible for generating physiologically diverse potassium channels in mammalian cells, mouse genomic clones have been isolated with a potassium channel complementary DNA, MBK1, that is homologous to the Drosophila potassium channel gene, Shaker. A family
B L Tempel et al.
Nature, 332(6167), 837-839 (1988-04-28)
Potassium channels comprise a diverse class of ion channels important for neuronal excitability and plasticity. The recent cloning of the Shaker locus from Drosophila melanogaster has provided a starting point for molecular studies of potassium channels. Predicted Shaker proteins appear

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