P8782
cis-2,3-Piperidinedicarboxylic acid
solid, ≥97% (NMR)
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About This Item
Empirical Formula (Hill Notation):
C7H11NO4
CAS Number:
Molecular Weight:
173.17
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
SMILES string
OC(=O)[C@@H]1CCCN[C@@H]1C(O)=O
assay
≥97% (NMR)
form
solid
color
white
solubility
H2O: ≥15 mg/mL
Gene Information
human ... GRIN1(2902), GRIN2A(2903), GRIN2B(2904), GRIN2C(2905), GRIN2D(2906), GRINA(2907)
Biochem/physiol Actions
NMDA receptor agonist at the glutamate recognition site.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
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M Neal et al.
Investigative ophthalmology & visual science, 39(5), 850-853 (1998-04-16)
To investigate the cellular origin of nitric oxide released from the rabbit retina in response to physiological stimulation with light. The release of nitric oxide from the retina was measured in rabbits anesthetized with urethane. An eye-cup was prepared and
T Priestley et al.
Molecular pharmacology, 46(6), 1191-1196 (1994-12-01)
The N-methyl-D-aspartate (NMDA) receptor is unique among the ligand-gated ion channels, in that the gating process requires the binding of two independent coagonists, glutamate and glycine. Receptor binding experiments have suggested that the coagonist recognition sites interact with one another
Daisuke Yokoyama et al.
Japanese journal of ophthalmology, 54(5), 458-466 (2010-11-06)
To determine whether photoreceptor degeneration in transgenic (Tg) rabbits carrying the Pro347Leu rhodopsin mutation alters the neural activity of the middle and inner retinal neurons. Multifocal electroretinograms (mfERGs) were recorded from eight 12-week-old Tg rabbits both before and after intravitreal
Manthan R Shah et al.
Experimental eye research, 90(2), 196-202 (2009-10-21)
When the eye is stimulated by a flickering light, the electroretinogram (ERG) and other electrophysiological responses in the visual pathway often exhibit period doubling. This phenomenon is manifested as an alternation in the shape of the response waveform from cycle
Nalini V Rangaswamy et al.
Investigative ophthalmology & visual science, 48(10), 4818-4828 (2007-09-28)
To determine flash and background colors that best isolate the photopic negative response (PhNR) and maximize its amplitude in the primate ERG. Photopic full-field flash ERGs were recorded from anesthetized macaque monkeys before and after pharmacologic blockade of Na(+)-dependent spiking
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