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P8925

Sigma-Aldrich

Octaethylene glycol monododecyl ether

≥98% (GC)

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Synonym(s):
C12E8, Dodecyl octaethylene glycol ether, Dodecyloctaglycol, Polyoxyethylene (8) lauryl ether
Linear Formula:
CH3(CH2)11(OCH2CH2)8OH
CAS Number:
3055-98-9
Molecular Weight:
538.75
Beilstein:
1893466
MDL number:
MFCD00043234
PubChem Substance ID:
24898996
NACRES:
NA.25

description

non-ionic

Assay

≥98% (GC)

form

solid

mol wt

average mol wt 66,000

aggregation number

123

CMC

0.11

SMILES string

CCCCCCCCCCCCOCCOCCOCCOCCOCCOCCOCCOCCO

InChI

1S/C28H58O9/c1-2-3-4-5-6-7-8-9-10-11-13-30-15-17-32-19-21-34-23-25-36-27-28-37-26-24-35-22-20-33-18-16-31-14-12-29/h29H,2-28H2,1H3

InChI key

YYELLDKEOUKVIQ-UHFFFAOYSA-N

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General description

Octaethylene glycol monododecyl ether is a nonionic detergent.

Application

Octaethylene glycol monododecyl ether has been used in a study to assess intestinal sodium transport mechanisms. It has also been used in a study to investigate interactions between dyes and surfactants in inkjet ink used for textiles.
Detergent used for the study of membrane proteins in a native-like state, e.g. ATPase. Used in a mixed micellar assay for lipoxygenase acting at neutral pH and for functional reconstitution of influenza virus envelopes.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Ju-Young Park et al.
Journal of oleo science, 60(12), 627-637 (2011-11-30)
Optimal preparation of inkjet ink should be possible through the elucidation of the relationship between dye/additive interactions and ink performance. In the present study, the interactions between the dyes and surfactant additives were investigated. To investigate the physical properties of
Cleyton C Domingues et al.
The Journal of membrane biology, 234(3), 195-205 (2010-03-27)
Transient lateral microdomains or lipid rafts play important roles in many physiological membrane-mediated cell processes. Detergent-resistant membranes (DRMs) are good models for the study of lipid rafts. Here we report that DRMs can be obtained by treating human erythrocytes with
G C Troiano et al.
Biophysical journal, 75(2), 880-888 (1998-07-24)
The effects of a nonionic surfactant, octaethyleneglycol mono n-dodecyl ether (C12E8), on the electroporation of planar bilayer lipid membranes made of the synthetic lipid 1-pamitoyl 2-oleoyl phosphatidylcholine (POPC), was studied. High-amplitude ( approximately 100-450 mV) rectangular voltage pulses were used
[Relationship between activity and tetraprotomeric structure of ion-transporting ATPases].
Kazuhiro Abe et al.
Seikagaku. The Journal of Japanese Biochemical Society, 79(6), 527-534 (2007-08-01)
L Tortech et al.
Biochimica et biophysica acta, 1514(1), 76-86 (2001-08-22)
Many attempts have been made to rationalize the use of detergents for membrane protein studies [J. Biol. Chem. 264 (1989) 4907]. The barrier properties of the detergent headgroup may be one parameter critically involved in protein protection. In this paper
View All Related Papers

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