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Merck
CN

PENB

Sigma-Aldrich

Penicillin G benzathine salt hydrate

~1200 U/mg

Synonym(s):

Benzylpenicillin benzathine salt hydrate

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About This Item

Empirical Formula (Hill Notation):
C32H36N4O8S2 · C16H20N2 · xH2O
CAS Number:
1538-09-6
Molecular Weight:
909.12 (anhydrous basis)
EC Number:
216-260-5
MDL number:
MFCD11045933
UNSPSC Code:
51101500

Key Documents

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specific activity

~1200 U/mg

SMILES string

O.C(CNCc1ccccc1)NCc2ccccc2.CC3(C)S[C@@H]4[C@H](NC(=O)Cc5ccccc5)C(=O)N4[C@H]3C(O)=O.CC6(C)S[C@@H]7[C@H](NC(=O)Cc8ccccc8)C(=O)N7[C@H]6C(O)=O

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General description

Chemical structure: ß-lactam

Pictograms

Health hazardExclamation mark
GHS08,GHS07

Signal Word

Danger

Hazard Statements

H302,H334

Precautionary Statements

P261 - P342 + P311

Hazard Classifications

Acute Tox. 4 Oral - Resp. Sens. 1

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

监管及禁止进口产品

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Certificates of Analysis (COA)

Lot/Batch Number
016F0354
050H0450

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Azithromycin versus penicillin G benzathine for early syphilis.
Xiang-Sheng Chen
Sexually transmitted diseases, 39(11), 900-901 (2012-10-13)
Arlene C Seña et al.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 56(3), 420-422 (2012-11-03)
Persistent nontreponemal titers after treatment are common among patients with early syphilis. We retreated 82 human immunodeficiency virus-negative early syphilis participants who were serofast at 6 months using benzathine penicillin. Only 27% exhibited serological response after retreatment and after an
An uncommon cause of ulceroinfiltrative gastric wall thickening in a young patient.
Young Chul Kim et al.
Gastroenterology, 143(5), e6-e7 (2012-09-27)
[Venous mesenteric infarction revealing tertiary syphilis].
S Bouomrani et al.
Medecine et maladies infectieuses, 43(2), 91-92 (2013-03-12)
D E Cousins et al.
International journal of STD & AIDS, 23(9), 632-634 (2012-10-04)
The evolution of treatment guidelines for early syphilis to single-dose benzathine penicillin regardless of HIV status has been controversial in the UK. We describe the treatment response in patients treated by current and previous regimens of benzathine penicillin for early
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