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Merck
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PENP

Penicillin G procaine salt hydrate

~1000 U/mg

Synonym(s):

Benzylpenicillin procaine salt, Procaine penicilline G hydrate

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About This Item

Linear Formula:
C16H18N2O4S · C13H20N2O2· xH2O
CAS Number:
Molecular Weight:
570.70 (anhydrous basis)
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
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InChI

1S/C16H18N2O4S.C13H20N2O2.H2O/c1-16(2)12(15(21)22)18-13(20)11(14(18)23-16)17-10(19)8-9-6-4-3-5-7-9;1-3-15(4-2)9-10-17-13(16)11-5-7-12(14)8-6-11;/h3-7,11-12,14H,8H2,1-2H3,(H,17,19)(H,21,22);5-8H,3-4,9-10,14H2,1-2H3;1H2/t11-,12+,14-;;/m1../s1

SMILES string

O.CCN(CC)CCOC(=O)c1ccc(N)cc1.CC2(C)S[C@@H]3[C@H](NC(=O)Cc4ccccc4)C(=O)N3[C@H]2C(O)=O

InChI key

KZDCMKVLEYCGQX-UDPGNSCCSA-N

specific activity

~1000 U/mg

antibiotic activity spectrum

Gram-negative bacteria, Gram-positive bacteria

mode of action

cell wall synthesis | interferes

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General description

Chemical structure: β-lactam

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Skin Sens. 1

Storage Class

11 - Combustible Solids

wgk

WGK 1

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Regulatory Information

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Secondary syphilis presenting in a red tattoo.
Jing Yuan et al.
European journal of dermatology : EJD, 20(4), 544-545 (2010-06-05)
A lethal injection?
Deepak Arumugam et al.
Lancet (London, England), 379(9814), 492-492 (2012-02-07)
Megan I Kaplan et al.
Journal of the American Veterinary Medical Association, 238(4), 507-510 (2011-02-16)
2 dogs and a cat were inadvertently given penicillin G procaine-penicillin G benzathine IV instead of propofol during induction of anesthesia for routine dental prophylaxis. One dog and the cat required hospitalization because of severe neurologic impairment and cardiopulmonary arrest
Kevin E Washburn et al.
Journal of the American Veterinary Medical Association, 234(9), 1162-1166 (2009-05-02)
To compare the effectiveness of 3 treatment regimens for small ruminants with caseous lymphadenitis. Randomized clinical trial. 44 client-owned sheep and goats. Aspirates were obtained from 48 lesions of 44 enrolled animals and submitted for bacterial culture. Animals were randomly
[Gastric syphilis: report of a case].
Yun DONG et al.
Zhonghua bing li xue za zhi = Chinese journal of pathology, 40(3), 198-199 (2011-05-18)

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