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PENP

Sigma-Aldrich

Penicillin G procaine salt hydrate

~1000 U/mg

Synonym(s):

Benzylpenicillin procaine salt, Procaine penicilline G hydrate

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About This Item

Linear Formula:
C16H18N2O4S · C13H20N2O2· xH2O
CAS Number:
6130-64-9
Molecular Weight:
570.70 (anhydrous basis)
MDL number:
MFCD00150771
UNSPSC Code:
12352200
PubChem Substance ID:
329820360

Key Documents

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specific activity

~1000 U/mg

antibiotic activity spectrum

Gram-negative bacteria
Gram-positive bacteria

Mode of action

cell wall synthesis | interferes

SMILES string

O.CCN(CC)CCOC(=O)c1ccc(N)cc1.CC2(C)S[C@@H]3[C@H](NC(=O)Cc4ccccc4)C(=O)N3[C@H]2C(O)=O

InChI

1S/C16H18N2O4S.C13H20N2O2.H2O/c1-16(2)12(15(21)22)18-13(20)11(14(18)23-16)17-10(19)8-9-6-4-3-5-7-9;1-3-15(4-2)9-10-17-13(16)11-5-7-12(14)8-6-11;/h3-7,11-12,14H,8H2,1-2H3,(H,17,19)(H,21,22);5-8H,3-4,9-10,14H2,1-2H3;1H2/t11-,12+,14-;;/m1../s1

InChI key

KZDCMKVLEYCGQX-UDPGNSCCSA-N

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General description

Chemical structure: ß-lactam

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H317

Hazard Classifications

Skin Sens. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
021K1046
109C07291
118C0098
109C0729
054K0521

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A L Chicoine et al.
Journal of veterinary pharmacology and therapeutics, 32(3), 289-295 (2009-08-04)
This paper describes the pharmacokinetic profile of procaine penicillin G after intraperitoneal (IP) administration in eight lactating dairy cows. Procaine pencillin G (PPG, 21 000 IU/kg) was deposited into the abdominal cavity of each cow following an incision in the
Sabine Mann et al.
Foodborne pathogens and disease, 8(8), 861-867 (2011-03-09)
The objective of this longitudinal controlled trial was to determine the effect of systemic treatment with ceftiofur on antimicrobial susceptibility of fecal Escherichia coli isolates in dairy cows. Cows with metritis or interdigital necrobacillosis requiring systemic antimicrobial treatment were sequentially
U Kayabas et al.
Chemotherapy, 58(1), 34-43 (2012-02-22)
Cutaneous anthrax (CA) is the most common clinical presentation in human anthrax, but the duration of antibiotic therapy in naturally occurring CA is controversial. The aim of this study was to compare the clinical outcomes of patients receiving antibiotic treatment
Mehmet Doganay et al.
Journal of infection and public health, 3(3), 98-105 (2010-09-28)
Anthrax is still an endemic disease in some countries in the world and has become a re-emerging disease in western countries with recent intentional outbreak. The aim of this study was to review our clinical experience with cutaneous anthrax cases.
Carsten Krüger et al.
World journal of pediatrics : WJP, 6(2), 125-131 (2010-05-22)
With 700,000 to 1.5 million new cases annually, congenital syphilis remains a major infectious cause of morbidity and mortality in neonates, infants and children in resource-poor countries. We therefore analyzed the extent of congenital syphilis in the pediatric patient population
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