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Merck
CN

PLA0050

Sigma-Aldrich

Goat anti-RFC5 Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.

Synonym(s):

36-kDa subunit, 36.5 kD subunit, 36.5kDa, A1 36 kDa subunit, Activator 1 36 kDa subunit, Activator 1 subunit 5, RF-C 36 kDa subunit, RFC, RFC36, Replication factor C 36 kDa subunit, replication factor C, replication factor C (activator 1) 5, replication factor C (activator 1) 5 (36.5kD)

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About This Item

UNSPSC Code:
12352203

Key Documents

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biological source

goat

Quality Level

100

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

species reactivity

human

technique(s)

western blot: 1:500-1:2,500

accession no.

NP_031396.1

UniProt accession no.

P40937

shipped in

wet ice

storage temp.

2-8°C

Gene Information

goat ... RFC5(5985)

Immunogen

The epitope recognized by PLA0050 maps to a region between residues 1 and 50 of human Replication Factor C subunit 5 using the numbering given in entry NP_031396.1 (GeneID 5985).

Physical form

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% sodium azide

Other Notes

The Replication factor C (RFC) heteropentamer includes RFC1, RFC2, RFC3, RFC4, and RFC5. The RFC heteropentamer is part of the multiprotein DNA replicase that functions to replicate DNA prior to cell division and repair DNA damage. RFC is the clamp loader ATPase associated with the DNA replicase. As the clamp loader, RFC uses ATP to recruit, open, and close the PCNA ring to link it to DNA for replication and repair. RFC5 is the 36kDa subunit of RFC that forms a core complex with RFC2 and RFC4 and can interact with the C-terminal region of PCNA.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
1

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