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Merck
CN

PLA0052

Sigma-Aldrich

Rabbit anti-Phospho Rad17 (S645) Antibody, Affinity Purified

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Synonym(s):

CCYC, HRAD17, R24L, RAD1 (S. pombe) homolog, RAD1 homolog, RAD17 homolog, RAD17 homolog (S. pombe), RAD17Sp, RF-C activator 1 homolog, RF-C/activator 1 homolog, Rad17-like protein, Rad24, cell cycle checkpoint protein (RAD17)

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

Key Documents

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biological source

rabbit

Quality Level

100

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

species reactivity

mouse, human

concentration

1 mg/mL

technique(s)

immunohistochemistry: 1:500-1:2,000
western blot: 1:1,000-1:5,000

accession no.

NP_002864.1

shipped in

wet ice

storage temp.

2-8°C

Gene Information

human ... RAD17(5884)

Immunogen

Immunogen for PLA0052 was a phosphorylated synthetic peptide, which represented a portion of human Rad17 (GeneID 5884) around serine 645 according to the numbering given in entry NP_002864.1.

Physical form

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% sodium azide

Other Notes

Rad17 is a cell cycle checkpoint protein that associates with the RFC complex to recruit the 9-1-1 complex (Rad9, Hus1, Rad1) to sites of DNA damage. At DNA lesions, Rad17 and RFC aid in the activation of Chk2 by ATM and ATRIP to trigger the checkpoint signaling cascade for G2 arrest.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Lot/Batch Number
2

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