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Merck
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PLA0058

Rabbit anti-Rad50 Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.

Synonym(s):

NBSLD, RAD50 (S. cerevisiae) homolog, RAD50 homolog, RAD50 homolog (S. cerevisiae), RAD50-2, RAD502, double strand break repair protein, hRad50

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203
Species reactivity:
human
Technique(s):
immunoprecipitation (IP): 1- 4 μg/mg, western blot: 1:1,000-1:5,000
Application:
IP, WB
Citations:
-

Key Documents

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biological source

rabbit

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

species reactivity

human

technique(s)

immunoprecipitation (IP): 1- 4 μg/mg, western blot: 1:1,000-1:5,000

accession no.

NP_005723.2

UniProt accession no.

Q92878

shipped in

wet ice

storage temp.

2-8°C

target post-translational modification

unmodified

Quality Level

100

Gene Information

rabbit ... Rad50(10111)

Immunogen

The epitope recognized by PLA0058 maps to a region between residues 50 and 100 of human Rad50 using the numbering given in entry NP_005723.2 (GeneID 10111).

Physical form

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% sodium azide

Other Notes

Rad50 is a component of the Mre11-Rad50-Nbs1 (MRN) complex that repairs DNA double strand breaks during DNA damage and homologous recombination and activates the S-phase checkpoint. Rad50 shows structural similarity to the structural maintenance of chromosomes (SMC) family of proteins. Rad50 has been shown to directly interact with BRCA2, TERF2IP, and ATM.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

12 - Non Combustible Liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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