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Merck
CN

PLA0090

Sigma-Aldrich

Rabbit anti-RFC4 Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.

Synonym(s):

37kDa, A1, A1 37 kDa subunit, RF-C 37 kDa subunit, RFC 37 kDa subunit, RFC37, activator 1 37 kDa subunit, activator 1 subunit 4, replication factor C (activator 1) 4, replication factor C (activator 1) 4 (37kD), replication factor C 37 kDa subunit

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About This Item

UNSPSC Code:
12352203

Key Documents

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biological source

rabbit

Quality Level

100

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

species reactivity

human

technique(s)

western blot: 1:1,000-1:10,000

accession no.

NP_002907.1

UniProt accession no.

P35249

shipped in

wet ice

storage temp.

2-8°C

Gene Information

rabbit ... RFC4(5984)

Immunogen

The epitope recognized by PLA0090 maps to a region between residues 1 and 50 of human Replication Factor C subunit 4 using the numbering given in entry NP_002907.1 (GeneID 5984).

Physical form

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% sodium azide

Other Notes

The Replication factor C (RFC) heteropentamer includes RFC1, RFC2, RFC3, RFC4, and RFC5. The RFC heteropentamer is part of the multiprotein DNA replicase that functions to replicate DNA prior to cell division and repair DNA damage. RFC is the clamp loader ATPase associated with the DNA replicase. As the clamp loader, RFC uses ATP to recruit, open, and close the PCNA ring to link it to DNA for replication and repair. RFC4 is the 37 kDa subunit of RFC that is part of the core complex formed with RFC2 and RFC5.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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