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Merck
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PLA0115

Rabbit anti-DNA-PKcs Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.

Synonym(s):

DNA-PK catalytic subunit, DNA-PKcs, DNAPK, DNPK1, HYRC, HYRC1, IMD26, XRCC7, complementing 1, hyper-radiosensitivity of murine scid mutation, p350, p460

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203
Species reactivity:
human
Technique(s):
immunoprecipitation (IP): 2-5 μg/mg, western blot: 1:1,000- 1:10,000
Application:
IP, WB
Citations:
-

Key Documents

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biological source

rabbit

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

species reactivity

human

technique(s)

immunoprecipitation (IP): 2-5 μg/mg, western blot: 1:1,000- 1:10,000

accession no.

NP_008835.5

shipped in

wet ice

storage temp.

2-8°C

target post-translational modification

unmodified

Quality Level

100

Gene Information

rabbit ... DNA-PKcs(5591)

Immunogen

The epitope recognized by PLA0115 maps to a region between residues 2050 and 2100 of human DNA-Dependent Protein Kinase, catalytic subunit using the numbering given in entry NP_008835.5 (GeneID 5591).

Physical form

Tris-buffered Saline containing 0.1% BSA containing 0.09% Sodium Azide

Other Notes

DNA-PKcs is the catalytic subunit of a DNA-dependent serine-threonine protein kinase (DNA-PK). DNA-PK is a heterotrimer comprised of DNA-PKcs and the Ku709/Ku86 dimer. DNA-PK is involved in DNA damage repair and V(D)J recombination. DNA-PK phosphorylates Artemis, a protein required for nonhomologous end-joining and is necessary for the loading of Artemis on damaged DNA.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Lot/Batch Number
1

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