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Merck
CN

PLA0152

Sigma-Aldrich

Rabbit anti-JARID1A/RBP2 Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.

Synonym(s):

AT rich interactive domain 1A, AT rich interactive domain 1A (RBBP2-like), AT rich interactive domain 1A (RBP2-like), JARID1A, Jumonji, RBBP-2, RBBP2, RBP2, histone demethylase JARID1A, jumonji, jumonji/ARID domain-containing protein 1A, lysine (K)-specific demethylase 5A, retinoblastoma binding protein 2, retinoblastoma-binding protein 2

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
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biological source

rabbit

Quality Level

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

species reactivity

mouse, human

technique(s)

immunoprecipitation (IP): 2-10 μg/mg
western blot: 1:2,000- 1:10,000

accession no.

NP_005047.1

shipped in

wet ice

storage temp.

2-8°C

Gene Information

rabbit ... JARID1A/RBP2(5927)

Immunogen

The epitope recognized by PLA0152 maps to a region between residue 1640 and 1690 of human Jumonji/ARID Domain-Containing Protein 1A/Retinoblastoma Binding Protein 2 Homolog 1 using the numbering given in entry NP_001036068.1 (GeneID 5927).

Physical form

Tris-buffered Saline containing 0.1% BSA containing 0.09% Sodium Azide

Other Notes

JARID1A/RBP2 is a member of the jumonji (jmj) domain containing gene family of histone demethylases that plays a role in chromatin regulation and influences transcriptional activation and suppression. Some recently characterized members of the jmj family include JARID1A/RBP2, JARID1C, JMJD1A, JMJD1B, JMJD1C, JMJD2A, JMJD2C and JMJD2D. JARID1A/RBP2 functions to specifically demethylate lys-4 of histone 3 and interacts with the tumor suppressor protein pRb.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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