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Merck
CN

PLA0159

Sigma-Aldrich

Rabbit anti-Timeless Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.

Synonym(s):

TIM, TIM1, Tof1 homolog, Tof1 homolog (S. cerevisiae), hTIM, timeless (Drosophila) homolog, timeless circadian clock 1, timeless homolog, timeless homolog (Drosophila)

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

Key Documents

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biological source

rabbit

Quality Level

100

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

species reactivity

human

technique(s)

immunoprecipitation (IP): 2-10 μg/mg

accession no.

NP_003911.1

UniProt accession no.

Q9UNS1

shipped in

wet ice

storage temp.

2-8°C

Gene Information

rabbit ... Timeless(8914)

Immunogen

The epitope recognized by PLA0159 maps to a region between residue 1120 and 1170 of human Timeless using the numbering given in entry NP_003911.1 (GeneID 8914).

Physical form

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

Other Notes

Timeless was first identified in Drosophila as a transcriptional regulator involved in the fly circadian rhythm. In mice, humans and yeast, the homologs of drosophila timeless have been observed to play a role in the DNA damage checkpoint response. Human timeless has been shown to interact with the circadian clock protein cryptochrome 2 as well as the DNA checkpoint proteins Chk1 and the ATR-ATRIP complex suggesting a link between circadian rhythm and the cell cycle.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Lot/Batch Number
1

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