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Merck
CN

PLA0161

Rabbit anti-MOF/MYST1 Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.

Synonym(s):

FLJ14040, K(lysine) acetyltransferase 8, Lysine acetyltransferase 8, MOF, MOZ, MYST histone acetyltransferase 1, MYST-1, MYST1, SAS2 and TIP60 protein 1, YBF2/SAS3, ZC2HC8, hMOF, histone acetyltransferase MYST1, ortholog of Drosophila males absent on the first (MOF), probable histone acetyltransferase MYST1

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

Key Documents

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biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human, mouse

technique(s)

immunohistochemistry: 1:500- 1:2,000
immunoprecipitation (IP): 2-5 μg/mg
western blot: 1:1,000- 1:10,000

accession no.

BAB13924.1

shipped in

wet ice

storage temp.

2-8°C

target post-translational modification

unmodified

Gene Information

rabbit ... MOF/MYST1(84148)

Immunogen

The epitope recognized by PLA0161 maps to a region between residue 1 and 50 of human males absent on the first (MYST histone acetyltransferase 1) using the numbering given in entry BAB13924.1 (GeneID 84148).

Physical form

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

Other Notes

MOF is a member of the MYST family of histone acetyltransferases (HAT). MOF has been shown to be required for histone H4 lysine K16-specific acetylation. MOF interacts with ATM (ataxia-telangiectasia-mutated) and may participate in the activation of ATM in response to DNA damage.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Lot/Batch Number
2

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Mzwanele Ngubo et al.
Aging cell, 23(7), e14150-e14150 (2024-04-05)
Hutchinson-Gilford Progeria syndrome (HGPS) is a lethal premature aging disorder caused by a de novo heterozygous mutation that leads to the accumulation of a splicing isoform of Lamin A termed progerin. Progerin expression deregulates the organization of the nuclear lamina

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