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Merck
CN

PLA0187

Sigma-Aldrich

Rabbit anti-BAF53A Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.

Synonym(s):

53 kDa BRG1-associated factor A, ARPN-BETA, Actl6, Arp4, BAF complex 53 kDa subunit, BAF53, BAF53A, BRG1-associated factor, BRG1-associated factor 53A, INO80 complex subunit K, INO80K, actin-like 6A, actin-related protein 4, actin-related protein Baf53a, arpNbeta, hArpN beta

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

Key Documents

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biological source

rabbit

Quality Level

100

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

species reactivity

human, mouse

technique(s)

immunohistochemistry: 1:100-1:500
western blot: 1:2,000- 1:10,000

accession no.

NP_004292.1

shipped in

wet ice

storage temp.

2-8°C

Gene Information

rabbit ... BAF53A(86)

Immunogen

The epitope recognized by PLA0187 maps to a region between residue 25 and 75 of human BRG1-associated factor, 53 kDa subunit A using the numbering given in entry NP_004292.1 (GeneID 86).

Physical form

Tris-buffered Saline containing 0.1% BSA containing 0.09% Sodium Azide

Other Notes

BAF53A is a 53kd subunit of the BAF (BRG1/brm-associated factor) complex, a SWI/SNF chromatin remodeling and histone acetyltransferase complex that functions in the regulation of gene transcription. In the BAF complex, BAF53A is important to the ATPase activity of SMARCA4/BRG1 and the association of the BAF complex with chromatin. BAF53A also appears to be important to the formation of higher-order chromatin structure and has been shown to associate with mitotic chromosomes. Recently, BAF53A has been found to interact with p53 and repress p53-mediated gene transcription in a BRG1-independent manner.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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