All Photos(3)



Rabbit anti-cAbl Antibody, Affinity Purified

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c-ABL1, receptor tyrosine kinase, JTK7, proto-oncogene c-Abl, non-receptor tyrosine kinase, bcr/c-abl oncogene protein, c-abl oncogene 1, v-abl Abelson murine leukemia viral oncogene homolog 1, proto-oncogene tyrosine-protein kinase ABL1, ABL, p150, v-abl, c-ABL, bcr/abl, Abelson tyrosine-protein kinase 1, Abelson murine leukemia viral oncogene homolog 1

biological source


Quality Level

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies


Powered by Bethyl Laboratories, Inc.

species reactivity



immunofluorescence: 1:100-1:1,000
immunohistochemistry: 1:100- 1:1,000
immunoprecipitation (IP): 2- 5 μg/mg
western blot: 1:2,000- 1:10,000

accession no.


shipped in

wet ice

storage temp.


Gene Information

rabbit ... cAbl(25)


The epitope recognized by PLA0203 maps to a region between residue 550 and 600 of human v-abl Abelson murine leukemia viral oncogene homolog 1 using the numbering given in entry NP_005148.2 (GeneID 25).

Physical form

Tris-buffered Saline containing 0.1% BSA containing 0.09% Sodium Azide

Other Notes

c-Abl is the human cellular homolog of a the v-Abl viral oncogene. v-Abl was originally discovered as a mouse cell-derived sequence in the genome of the Abelson murine leukemia virus (A-MuLV), a transforming retrovirus isolated by the laboratory of Dr. H.T. Abelson. c-Abl is a tyrosine kinase from the Src-family of tyrosine kinases that localizes to both the cytoplasm and nucleus. It bears an SH2 (src-homology 2) and SH3 (src-homology 3) domain responsible for mediating c-Abl protein-protein interactions. c-Abl is implicated to play a role in multiple cellular processes such as cell cycle checkpoint signaling, apoptosis, cell differentiation, cell adhesion, and transcriptional regulation. Chromosomal translocations involving the c-Abl gene are associated with human leukemias.


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Storage Class Code

12 - Non Combustible Liquids



Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Certificate of Origin

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