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Merck
CN

PLA0209

Sigma-Aldrich

Rabbit anti-DBF4 Antibody, Affinity Purified

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About This Item

UNSPSC Code:
12352203
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biological source

rabbit

Quality Level

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

species reactivity

human, guinea pig, rat, dog, horse, pig, mouse, primate, rabbit, bovine, rhesus monkey

concentration

1 mg/mL

technique(s)

immunoprecipitation (IP): 2- 5 μg/mg

accession no.

NP_006707.1

UniProt accession no.

shipped in

wet ice

storage temp.

2-8°C

Gene Information

rabbit ... DBF4(10926)

Immunogen

The epitope recognized by PLA0209 maps to a region between residue 100 and 150 of human DBF4 (activator of S phase kinase) using the numbering given in entry NP_006707.1 (GeneID 10926).

Physical form

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

Other Notes

The DBF4 gene was originally identified in replication mutants of S. cerevisiae that exhibited a “dumbbell former” phenotype characterized by a cell with a single large bud. The human homolog was later isolated in a two-hybrid screen for proteins that interact with the human Cdc7-related kinase (huCdc7), a conserved kinase that phosphorylates MCM2 and MCM3 and is required for the G1/S transition. DBF4 functions as a regulatory subunit for the human Cdc7 kinase and is essential for the initiation of DNA repair.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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