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Merck
CN

PLA0245

Sigma-Aldrich

Rabbit anti-AKT2 Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.

Synonym(s):

HIHGHH, PKB beta, PKBB, PKBBETA, PRKBB, RAC-BETA, RAC-PK-beta, murine thymoma viral (v-akt) homolog-2, protein kinase Akt-2, protein kinase B beta, putative v-akt murine thymoma viral oncoprotein 2, rac protein kinase beta, v-akt murine thymoma viral oncogene homolog 2

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

Key Documents

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biological source

rabbit

Quality Level

100

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

species reactivity

human

technique(s)

immunoprecipitation (IP): 5-10 μg/mg
western blot: 1:2,000- 1:10,000

accession no.

NP_001617.

UniProt accession no.

P31751

shipped in

wet ice

storage temp.

2-8°C

Gene Information

rabbit ... AKT2(208)

Immunogen

The epitope recognized by PLA0245 maps to a region between residue 431 and 481 of human v-akt murine thymoma viral oncogene homolog 2 using the numbering given in entry NP_001617.1 (GeneID 208).

Physical form

Tris-buffered Saline containing 0.1% BSA containing 0.09% Sodium Azide

Other Notes

AKT2 is one of 3 highly homologous serine/threonine kinases which include AKT1, AKT2, and AKT3. AKT2 has been found play an integral role in the insulin signaling pathway and is implicated in cancer development.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
1

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Wei Kang et al.
Journal of translational medicine, 12, 281-281 (2014-10-08)
Aberrant AKT activation contributes to gastric cancer cell survival and chemotherapy resistance, however its regulation is poorly understood. microRNAs have been established to be important regulators in gastric carcinogenesis. Here, we showed the functional role and putative target of let-7b
Zuoren Yu et al.
Oncotarget, 5(4), 1083-1090 (2014-03-25)
The serine threonine kinase Akt1 has been implicated in the control of cellular metabolism, survival and growth. Herein, disruption of the ubiquitously expressed member of the Akt family of genes, Akt1, in the mouse, demonstrates a requirement for Akt1 in

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