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About This Item
NACRES:
NA.41
UNSPSC Code:
12352203
biological source
rabbit
Quality Level
antibody form
affinity purified immunoglobulin
antibody product type
primary antibodies
species reactivity
human, mouse
technique(s)
immunohistochemistry: 1:1,000-1:5,000, immunoprecipitation (IP): 2- 10 μg/mg
accession no.
NP_002746.1
shipped in
wet ice
storage temp.
2-8°C
Gene Information
human ... MAP2K1(5604)
Immunogen
The epitope recognized by PLA0285 maps to a region of human MAPK/ERK kinase 1 (dual specificity mitogen-activiated protein kinase kinase 1) surrounding threonine 286 using the numbering given in entry NP_002746.1 (Gene ID 5604) when the threonine residue is phosphorylated.
Physical form
Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Other Notes
MEK1 is an activator and kinase for MAP and ERK kinases. It is a serine/threonine kinase essential to the MAP kinase signal transduction pathway which is involved in a multitude of cellular processes such as proliferation, differentiation, gene activation, and development. MEK1 displays 85% identity with MEK2. Although MEK1 and MEK2 have been found to be functionally similar, they may serve non-redundant functions. Both are required for cellular proliferation and may play a role in tumorigenesis.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
12 - Non Combustible Liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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