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Merck
CN

PLA0293

Goat anti-Lasu1/Ureb1 Antibody, Affinity Purified

Synonym(s):

ARF-BP1, ARF-binding protein 1, BJ-HCC-24 tumor antigen, HECT, HECT domain protein LASU1, HECTH9, HSPC272, Ib772, KIAA0312, LASU1, MULE, Mcl-1 ubiquitin ligase E3, UBA and WWE domain containing 1, UBA and WWE domain-containing protein 1, URE-B1, URE-binding protein 1, UREB1, homologous to E6AP carboxyl terminus homologous protein 9, large structure of UREB1, upstream regulatory element-binding protein 1

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203

Key Documents

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biological source

goat

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

species reactivity

human

technique(s)

western blot: 1:500- 1:2,500

accession no.

NP_113584.3

shipped in

wet ice

storage temp.

2-8°C

Quality Level

100

Gene Information

goat ... Lasu1/Ureb1(10075)

Immunogen

The epitope recognized by PLA0293 maps to a region between residue 2250 and 2300 of human HECT domain protein LASU1/Upstream Regulatory Element Binding Protein 1 using the numbering given in entry NP_113584.3 (GeneID 10075).

Physical form

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

Other Notes

The conjugation of ubiquitin to proteins is an important means to regulate protein activity for many cellular processes by tagging them for degradation. Lasu1/Ureb1 is an E3 ubiquitin protein ligase that mediates the ubiquitination of core histones, Mcl-1, Cdc6, and p53. Lasu1/Ureb1 expression is regulated during spermatogenesis and appears to play a role in chromatin modification in germ cells as well as other tissues.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

12 - Non Combustible Liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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