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Merck
CN

PLA0296

Goat anti-FUS Antibody, Affinity Purified

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Synonym(s):

75 kDa DNA-pairing protein, ALS6, ETM4, FUS1, HNRNPP2, POMP75, TLS, amyotrophic lateral sclerosis 6, derived from t(12;16) malignant liposarcoma, fus-like protein, fused in sarcoma, fusion, fusion (involved in t(12;16) in malignant liposarcoma), fusion gene in myxoid liposarcoma, heterogeneous nuclear ribonucleoprotein P2, hnRNP-P2, oncogene FUS, oncogene TLS, translocated in liposarcoma, translocated in liposarcoma protein

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203
Species reactivity:
human, mouse
Technique(s):
immunohistochemistry: 1:500-1:2,000, immunoprecipitation (IP): 2- 10 μg/mg, western blot: 1:2,000- 1:10,000
Application:
IHC, IP, WB
Citations:
-

Key Documents

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biological source

goat

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

species reactivity

human, mouse

technique(s)

immunohistochemistry: 1:500-1:2,000, immunoprecipitation (IP): 2- 10 μg/mg, western blot: 1:2,000- 1:10,000

accession no.

P35637

UniProt accession no.

P35637

shipped in

wet ice

storage temp.

2-8°C

target post-translational modification

unmodified

Quality Level

100

Gene Information

goat ... FUS(2521)

Immunogen

The epitope recognized by PLA0296 maps to a region between residue 1 and 50 of human Fusion (involved in t(12;16) in malignant liposarcoma) using the numbering given in entry P35637 (GeneID 2521).

Physical form

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

Other Notes

FUS has been identified as a frequent translocation fusion partner of various transcription factors. FUS fusion genes have been shown to be associated with multiple tumor types which include liposarcoma, leukemia, histocytoma, and sarcoma. FUS is a multifunctional RNA-binding protein that associates with the nuclear matrix and Cajal bodies and appears to play a role in splicesome assembly, pre-mRNA splicing, DNA repair, transcriptional regulation and homologous recombination.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

12 - Non Combustible Liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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