Skip to Content
Merck
CN

PZ0124

CP-66713

≥98% (HPLC)

Synonym(s):

8-chloro-1-phenyl-[1,2,4]triazolo[4,3-a]quinoxalin-4-amine, PF-1716311

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

Empirical Formula (Hill Notation):
C15H10ClN5
CAS Number:
91896-57-0
Molecular Weight:
295.73
NACRES:
NA.77
PubChem Substance ID:
329823714
UNSPSC Code:
51111800
MDL number:
MFCD17215961

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

InChI

1S/C15H10ClN5/c16-10-6-7-11-12(8-10)21-14(9-4-2-1-3-5-9)19-20-15(21)13(17)18-11/h1-8H,(H2,17,18)

SMILES string

Nc1nc2ccc(Cl)cc2n3c(nnc13)-c4ccccc4

InChI key

PBENJWAFQLORQL-UHFFFAOYSA-N

assay

≥98% (HPLC)

form

powder

color

white to off-white

solubility

DMSO: ≥5 mg/mL

storage temp.

2-8°C

Quality Level

100

Biochem/physiol Actions

CP-66713 is an adenosine A2 receptor antagonist.

Features and Benefits

This compound is featured on the Adenosine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

新产品
This item has

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
070M4729

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

S Fujii et al.
Neuroscience letters, 148(1-2), 148-150 (1992-12-14)
The effects of the adenosine A2 receptor antagonist CP-66713 on the reversal of long-term potentiation (LTP) were studied in CA1 neurons of guinea pig hippocampal slices. Reduction of LTP (depotentiation, DP) was effected by delivering a train of low-frequency afferent
E M O'Kane et al.
European journal of pharmacology, 362(1), 17-25 (1998-12-29)
Previous work has been carried out on the effects of adenosine on transmitter release and on the excitability of postsynaptic neurones, but little is known about the effects of adenosine on the coupling between the two. In this study, we
T Matsugi et al.
Investigative ophthalmology & visual science, 38(13), 2695-2701 (1998-01-07)
To investigate the effect of adenosine on the contractile tone of cultured bovine retinal pericytes. Changes in the contractile tone were quantified as the changes in the summed length of wrinkles induced by pericytes on the silicone surface on which
H Fuder et al.
Naunyn-Schmiedeberg's archives of pharmacology, 345(4), 417-423 (1992-04-01)
To investigate whether endogenous purinoceptor agonists affect the sympathetic neurotransmission in the rat isolated iris, and to classify the purinoceptors modulating exocytotic [3H]-noradrenaline release, we have determined the effect of adenosine receptor antagonists on, and the relative potency of selected
M Suzuki et al.
Japanese journal of pharmacology, 68(1), 119-123 (1995-05-01)
We examined the effects of 1,3-dipropyl-8-cyclopentylxanthine (DPCPX) and (R)-7,8-dihydro-8-ethyl-2-(3-noradamantyl)-4-propyl-1H-imidazo[2,1 -i]purin- 5(4H)-one (KF20274), selective adenosine A1-receptor antagonists, on the gastrointestinal propulsion in rats, as compared with those of the laxative bisacodyl. DPCPX and KF20274 (p.o.) dose-dependently increased the fecal pellet output
View All Related Papers

Articles

Adenosine Receptors

We offers many products related to adenosine receptors for your research needs.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service