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Merck
CN

PZ0223

PF-04991532

≥98% (HPLC)

Synonym(s):

6-[[(2S)-3-Cyclopentyl-1-oxo-2-[4-(trifluoromethyl)-1H-imidazol-1-yl]propyl]amino]-3-pyridinecarboxylic acid, PF 04991532

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About This Item

Empirical Formula (Hill Notation):
C18H19F3N4O3
CAS Number:
1215197-37-7
Molecular Weight:
396.36
UNSPSC Code:
51111800
NACRES:
NA.77

Key Documents

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SMILES string

FC(F)(F)c1nc[n](c1)[C@@H](CC3CCCC3)C(=O)Nc2ncc(cc2)C(=O)O

InChI

1S/C18H19F3N4O3/c19-18(20,21)14-9-25(10-23-14)13(7-11-3-1-2-4-11)16(26)24-15-6-5-12(8-22-15)17(27)28/h5-6,8-11,13H,1-4,7H2,(H,27,28)(H,22,24,26)/t13-/m0/s1

InChI key

GKMLFBRLRVQVJO-ZDUSSCGKSA-N

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 20 mg/mL, clear

storage temp.

room temp

Quality Level

100

Biochem/physiol Actions

PF-04991532 is a potent and hepatoselective glucokinase activator that reduces mean daily glucose (MDG), fasting plasma glucose (FPG) and glucose excursion in humans.
PF-04991532 is a potent and hepatoselective glucokinase activator.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
0000016181
044M4733V

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