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Merck
CN

PZ0268

AG-17724

≥98% (HPLC)

Synonym(s):

(R)-6-Fluoro--[(2-naphthalenylcarbonyl)amino]-1H-benzimidazole-2-propanoic acid, AG 17724

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About This Item

Empirical Formula (Hill Notation):
C21H16FN3O3
CAS Number:
Molecular Weight:
377.37
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder
Quality level:
Technical Service
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Quality Level

assay

≥98% (HPLC)

form

powder

color

white to light brown

solubility

DMSO: 20 mg/mL, clear (warmed)

storage temp.

room temp

SMILES string

OC([C@H](NC(C1=CC(C=CC=C2)=C2C=C1)=O)CC3=NC4=C(C=CC(F)=C4)N3)=O

InChI

1S/C21H16FN3O3/c22-15-7-8-16-17(10-15)24-19(23-16)11-18(21(27)28)25-20(26)14-6-5-12-3-1-2-4-13(12)9-14/h1-10,18H,11H2,(H,23,24)(H,25,26)(H,27,28)/t18-/m1/s1

InChI key

NKMPZFCFXCJBEY-GOSISDBHSA-N

Biochem/physiol Actions

AG-17724 is a potent peptidyl-prolyl isomerase (PPIase) Pin1 inhibitor.


pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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Articles

Cell cycle phases (G1, S, G2, M) regulate cell growth, DNA replication, and division in proliferating cells.





Global Trade Item Number

SKUGTIN
PZ0268-5MG04061833066355
PZ0268-25MG04061833066348