PZ0364
DIBA-1
≥97% (NMR)
别名:
2,2′-Disulfanediylbis(N-(4-sulfamoylphenyl)benzamide, 2,2′-Dithiobis[N-[4-(aminosulfonyl)phenyl]benzamide], NSC 654077, PD022551
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关于此项目
Assay:
≥97% (NMR)
Form:
powder
Quality Segment
assay
≥97% (NMR)
form
powder
color
white to light brown
solubility
DMSO: 2 mg/mL, clear
storage temp.
room temp
SMILES string
[S](=O)(=O)(N)c1ccc(cc1)NC(=O)c2c(cccc2)SSc3c(cccc3)C(=O)Nc4ccc(cc4)[S](=O)(=O)N
InChI
1S/C26H22N4O6S4/c27-39(33,34)19-13-9-17(10-14-19)29-25(31)21-5-1-3-7-23(21)37-38-24-8-4-2-6-22(24)26(32)30-18-11-15-20(16-12-18)40(28,35)36/h1-16H,(H,29,31)(H,30,32)(H2,27,33,34)(H2,28,35,36)
InChI key
FVGJPHFQQMQGFQ-UHFFFAOYSA-N
Biochem/physiol Actions
DIBA-1 (2,2′-dithiobisbenzamide-1) is a disulfide that interacts with zinc fingers as a zinc ejector. It has been shown to interact with many zinc finger containing proteins, including HIV-1 nucleocapsid and the estrogen receptor. DIBA-1 has been studied as a candidate for the treatment of AIDS and also breast cancer. In one study DIBA restored tamoxifen sensitivity in resistant breast cancer.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable