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Q1626

Quene 1-AM

Synonym(s):

8-bis(Carboxymethyl)amino-2-[2-(2-bis(carboxymethyl)aminophenyl)ethenyl]-6-methoxyquinoline tetra(acetoxymethyl) ester

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About This Item

Empirical Formula (Hill Notation):
C38H41N3O17
CAS Number:
86293-31-4
Molecular Weight:
811.74
NACRES:
NA.77
PubChem Substance ID:
24899324
UNSPSC Code:
12352202
MDL number:
MFCD00079535
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shipped in

dry ice

storage temp.

−20°C

SMILES string

COc1cc(N(CC(=O)OCOC(C)=O)CC(=O)OCOC(C)=O)c2nc(\C=C\c3ccccc3N(CC(=O)OCOC(C)=O)CC(=O)OCOC(C)=O)ccc2c1

InChI

1S/C38H41N3O17/c1-24(42)51-20-55-34(46)16-40(17-35(47)56-21-52-25(2)43)32-9-7-6-8-28(32)10-12-30-13-11-29-14-31(50-5)15-33(38(29)39-30)41(18-36(48)57-22-53-26(3)44)19-37(49)58-23-54-27(4)45/h6-15H,16-23H2,1-5H3/b12-10+

InChI key

LEFGNZVSFRGPIG-ZRDIBKRKSA-N

Application

Fluorescent probe for intracellular pH.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
128H0634
128H0635
128H0474

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J Rogers et al.
FEBS letters, 161(1), 21-27 (1983-09-05)
Photometric fluorescence microscopy has been used to measure intracellular pH (pHi) and free calcium concentrations [( Ca]i) in individual mouse thymocytes and 2H3 rat basophil leukaemic cells containing indicators for pH (quene 1) or calcium (quin 2). The pHi and
J Rogers et al.
The Journal of biological chemistry, 258(10), 5994-5997 (1983-05-25)
A new fluorescent intracellular pH indicator is described ("quene 1") which is related to the tetracarboxylate Ca2+ indicator based on the quinoline fluorophor ("quin 2"). Quene 1 has excitation and emission maxima at 390 and 530 nm, respectively, and shows

Global Trade Item Number

SKUGTIN
Q1626-1MG04061826226407