Key Documents

View All Documentation

Q3251

Quinacrine dihydrochloride

Name: Quinacrine dihydrochloride
Brand: SIGMA

≥90% (TLC), powder, MAO-A/B inhibitor

Synonym(s):

6-Chloro-9-(4-diethylamino-1-methylbutylamino)-2-methoxyacridine dihydrochloride, Atebrin dihydrochloride, Mepacrine dihydrochloride

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):

C₂₃H₃₀ClN₃O · 2HCl

CAS Number:

69-05-6

Molecular Weight:

472.88

NACRES:

NA.77

PubChem Substance ID:

24278192

UNSPSC Code:

12352101

EC Number:

200-700-8

MDL number:

MFCD00012659

Beilstein/REAXYS Number:

4834013

Assay:

≥90%

Form:

powder

Quality level:

100

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

Properties

Product Name

Quinacrine dihydrochloride, ≥90%

biological source

synthetic

Quality Level

100

assay

≥90%

form

powder

mp

257 °C

solubility

H₂O: soluble, clear to hazy

originator

Bayer

SMILES string

Cl[H].Cl[H].CCN(CC)CCCC(C)Nc1c2ccc(Cl)cc2nc3ccc(OC)cc13

InChI

1S/C23H30ClN3O.2ClH/c1-5-27(6-2)13-7-8-16(3)25-23-19-11-9-17(24)14-22(19)26-21-12-10-18(28-4)15-20(21)23;;/h9-12,14-16H,5-8,13H2,1-4H3,(H,25,26);2*1H

InChI key

UDKVBVICMUEIKS-UHFFFAOYSA-N

Gene Information

human ... MAOA(4128), MAOB(4129)

Description

General description

Quinacrine is an acridine derivative and a potent antimalarial agent.

Application

Quinacrine dihydrochloride has been used:

in its uptake and accumulation studies in mouse lung slices using fluorescence microscope
in the staining of ATP vesicles in mesenchymal stem cells (MSCs)
in uptake-release assay for characterization of dense granule functionality of platelets

Biochem/physiol Actions

Quinacrine has anthelmintic functionality and used in the female sterilization. It is used to treat systemic lupus erythematosus and rheumatic diseases. Apart from malaria, Quinacrine is effective for treating giardia and tapeworm infections. It inhibits nicotinamide adenine dinucleotide phosphate (NADPH) oxidase activity in addition to monoamine oxidase inhibition.

Non-selective MAO-A/B inhibitor.

Features and Benefits

This compound was developed by Bayer. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Preparation Note

Stock solutions are stable for up to 60 h at 20°C.

Other Notes

This product is not assigned an expiration date or recommended retest date.

Still not finding the right product?

Explore all of our products under Quinacrine dihydrochloride

pictograms

GHS07

signalword

Warning

hcodes

H302

pcodes

P264 - P270 - P301 + P312 - P501

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Global Trade Item Number

SKU	GTIN
Q3251-100G	04061836687946
Q3251-25G	04061836687953