R2028
RHC 80267
≥98% (HPLC), solid
Synonym(s):
1,6-bis(Cyclohexyloximinocarbonylamino)hexane, U 57908
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About This Item
Empirical Formula (Hill Notation):
C20H34N4O4
CAS Number:
Molecular Weight:
394.51
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
41106300
MDL number:
Assay:
≥98% (HPLC)
Form:
solid
Quality Segment
assay
≥98% (HPLC)
form
solid
color
white
solubility
DMSO: 9 mg/mL
SMILES string
O=C(NCCCCCCNC(=O)O\N=C1/CCCCC1)O\N=C2/CCCCC2
InChI
1S/C20H34N4O4/c25-19(27-23-17-11-5-3-6-12-17)21-15-9-1-2-10-16-22-20(26)28-24-18-13-7-4-8-14-18/h1-16H2,(H,21,25)(H,22,26)
InChI key
RXSVYGIGWRDVQC-UHFFFAOYSA-N
Biochem/physiol Actions
RHC 80267 is a diacylglycerol (DAG) lipase inhibitor and an important second messenger in signal transduction pathways. RHC 80267 is generated by the hydrolysis of phosphatidylinositol (PI) and bPC by phospholipase C (PLC). DAG mediates the actions of a large number of hormones and cytokines by activating protein kinase C (PKC). A sustained elevation in intracellular DAG may cause neoplastic transformation.
RHC 80267 is a diacylglycerol (DAG) lipase inhibitor.
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Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
PPE (personal protective equipment)
Eyeshields, Gloves, type N95 (US)
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