R4529
Anti-Rattin antibody produced in rabbit
affinity isolated antibody, buffered aqueous solution
Synonym(s):
Anti-Humanin-like in rat
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About This Item
Conjugate:
unconjugated
Clone:
polyclonal
Application:
WB
Citations:
3
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
species reactivity
rat
technique(s)
western blot: 1:500
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
rat ... mt-Rnr2(170603)
General description
Rattin or RNR2 (RNA, ribosomal 45S cluster 2) is a subunit of the ribonucleoside diphosphate reductase. It is located on chromosome 14p12.
Immunogen
peptide corresponding to the rattin peptide (amino acids 20-35), which is not in the conserved region to humanin.
Biochem/physiol Actions
Rattin or RNR2 (RNA, ribosomal 45S cluster 2) helps in the synthesis of nucleotide precursors. It is responsible for the formation of the deoxyribonucleotides required for DNA synthesis. It is an important cofactor of HIV-1, that induces reverse transcription in MDMs (monocyte-derived macrophages).
Physical form
Solution of 1 mg/mL in phosphate buffered saline containing 0.02% sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Find documentation for the products that you have recently purchased in the Document Library.
Identification of the DNA damage-responsive element of RNR2 and evidence that four distinct cellular factors bind it
Elledge SJ and Davis RW, et al.
Molecular and Cellular Biology, 9(12), 5373-5386 (1989)
Application of yeast cells transformed with GFP expression constructs containing the RAD54 or RNR2 promoter as a test for the genotoxic potential of chemical substances
Afanassiev V, et al.
Mutation Research, 464(2), 297-308 (2000)
Manipulation of human minichromosomes to carry greater than megabase-sized chromosome inserts
Kuroiwa Y, et al.
Nature Biotechnology, 18(10), 1086-1090 (2000)
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