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Merck
CN

R5380

Sigma-Aldrich

N-Acetyl-Renin Substrate Tetradecapeptide porcine

≥97% (HPLC), suitable for MALDI-MS

Synonym(s):

Ac-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu-Leu-Val-Tyr-Ser

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About This Item

Empirical Formula (Hill Notation):
C87H125N21O21
CAS Number:
Molecular Weight:
1801.05
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
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Product Name

N-Acetyl-Renin Substrate Tetradecapeptide porcine, ≥97% (HPLC)

Quality Level

Assay

≥97% (HPLC)

form

powder

technique(s)

MALDI-MS: suitable

color

white

storage temp.

−20°C

SMILES string

CCC(C)C(NC(=O)C(Cc1ccc(O)cc1)NC(=O)C(NC(=O)C(CCCNC(N)=N)NC(=O)C(CC(O)=O)NC(C)=O)C(C)C)C(=O)NC(Cc2cnc[nH]2)C(=O)N3CCCC3C(=O)NC(Cc4ccccc4)C(=O)NC(Cc5cnc[nH]5)C(=O)NC(CC(C)C)C(=O)NC(CC(C)C)C(=O)NC(C(C)C)C(=O)NC(Cc6ccc(O)cc6)C(=O)NC(CO)C(O)=O

InChI

1S/C87H125N21O21/c1-12-49(10)72(107-80(122)63(36-53-24-28-57(112)29-25-53)102-82(124)70(47(6)7)105-73(115)58(20-16-30-92-87(88)89)96-78(120)65(39-69(113)114)95-50(11)110)84(126)103-66(38-55-41-91-44-94-55)85(127)108-31-17-21-68(108)81(123)100-61(34-51-18-14-13-15-19-51)75(117)99-64(37-54-40-90-43-93-54)77(119)97-59(32-45(2)3)74(116)98-60(33-46(4)5)79(121)106-71(48(8)9)83(125)101-62(35-52-22-26-56(111)27-23-52)76(118)104-67(42-109)86(128)129/h13-15,18-19,22-29,40-41,43-49,58-68,70-72,109,111-112H,12,16-17,20-21,30-39,42H2,1-11H3,(H,90,93)(H,91,94)(H,95,110)(H,96,120)(H,97,119)(H,98,116)(H,99,117)(H,100,123)(H,101,125)(H,102,124)(H,103,126)(H,104,118)(H,105,115)(H,106,121)(H,107,122)(H,113,114)(H,128,129)(H4,88,89,92)

InChI key

IUJUQXJOVSWPHY-UHFFFAOYSA-N

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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T C Cheng et al.
Protein science : a publication of the Protein Society, 8(11), 2474-2486 (1999-12-14)
A novel metallocarboxypeptidase (PfuCP) has been purified to homogeneity from the hyperthermophilic archaeon, Pyrococcus furiosus, with its intended use in C-terminal ladder sequencing of proteins and peptides at elevated temperatures. PfuCP was purified in its inactive state by the addition
Jadwiga Dudkiewicz-Wilczyńska et al.
Acta poloniae pharmaceutica, 61(3), 171-174 (2004-10-16)
A high-performance liquid chromatographic assay has been developed to the separation of angiotensin I, tetradecapeptide and the tetrapeptide Leu-Val-Tyr-Ser. This purpose is achieved in a single step, using HPLC technique in the reversed phase system. The method is based on
Khalid M Elased et al.
Hypertension (Dallas, Tex. : 1979), 46(4), 953-959 (2005-08-17)
This article demonstrates the applicability of quantitative proteomics to assays of proteolytic enzyme activity. A novel assay was developed for measurement of renin and angiotensin-converting enzyme (ACE) activity in plasma. The method was validated in animal models associated with alterations
C F Santos et al.
Journal of periodontology, 80(1), 130-139 (2009-02-21)
The systemic renin-angiotensin system (RAS) promotes the plasmatic production of angiotensin (Ang) II, which acts through interaction with specific receptors. There is growing evidence that local systems in various tissues and organs are capable of generating angiotensins independently of circulating

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