R7502
Roridin A from Myrothecium sp.
powder, ≥98% (TLC)
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About This Item
Empirical Formula (Hill Notation):
C29H40O9
CAS Number:
Molecular Weight:
532.62
UNSPSC Code:
12352200
PubChem Substance ID:
EC Number:
238-783-8
MDL number:
assay
≥98% (TLC)
form
powder
solubility
chloroform: ≥10 mg/mL, clear, colorless
storage temp.
−20°C
SMILES string
CC(O)C1OCCC(C)C(O)C(=O)OCC23CCC(C)=CC2OC4CC(OC(=O)\C=C\C=C\1)C3(C)C45CO5
signalword
Danger
hcodes
pcodes
Hazard Classifications
Acute Tox. 2 Oral
Storage Class
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
Regulatory Information
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T D Kimbrough et al.
Toxicology letters, 70(2), 165-170 (1994-02-01)
The ex vivo biophysical response of isolated rat aorta to T-2 toxin, diacetoxyscirpenol (DAS) and Roridin-A were determined. Roridin-A caused a dose-dependent relaxation of precontracted (30 mM KCl) aorta, while T-2 toxin and DAS were without effect. On the other
G Hunder et al.
Natural toxins, 2(3), 120-123 (1994-01-01)
Lethal doses of the trichothecene mycotoxins T-2 toxin (1.5 mg/kg), diacetoxyscirpenol (DAS; 2.3 mg/kg) or roridin A (1.3 mg/kg) were intravenously administered to rats. When rats were treated with either activated charcoal (Superchar liquid, Norit A; 1 g/kg, po) or
Zahidul Islam et al.
Toxicological sciences : an official journal of the Society of Toxicology, 98(2), 526-541 (2007-05-08)
Macrocyclic trichothecene mycotoxins produced by indoor air molds potentially contribute to symptoms associated with damp building illnesses. The purpose of this investigation was to determine (1) the kinetics of nasal inflammation and neurotoxicity after a single intranasal instillation of roridin