R9151
Rimantadine
solid
Synonym(s):
α-Methyl-1-adamantanemethylamine, remantadine
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About This Item
Empirical Formula (Hill Notation):
C12H21N
CAS Number:
Molecular Weight:
179.30
UNSPSC Code:
41116107
form
solid
mol wt
apparent mol wt 179.3
InChI
1S/C12H21N/c1-8(13)12-5-9-2-10(6-12)4-11(3-9)7-12/h8-11H,2-7,13H2,1H3
InChI key
UBCHPRBFMUDMNC-UHFFFAOYSA-N
Application
Antiviral.
Storage Class
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Márcia G Alves Galvão et al.
The Cochrane database of systematic reviews, 1, CD002745-CD002745 (2012-01-20)
The effectiveness and safety of amantadine (AMT) and rimantadine (RMT) for preventing and treating influenza A in adults has been systematically reviewed. However, little is known about these treatments in children and the elderly. To systematically review the effectiveness and
V A Shibnev et al.
Bulletin of experimental biology and medicine, 153(2), 233-235 (2012-07-21)
New adamantane derivatives with amino acid residues and other bifunctional compounds were synthesized and their antiviral activity towards influenza A(H1N1)pdm and A(H3N2) viruses was studied. Some of these adamantane derivatives completely suppressed replication of remantadine-resistant influenza A virus strains.
Rimantadine: a clinical perspective. .
Wintermeyer, S. M. et al.
Pharmacotherapy, 29, 299-299 (1995)