RAB0200
Gastrin EIA Kit
for serum, plasma, culture supernatant and cell lysates
Synonym(s):
Gastrin
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About This Item
UNSPSC Code:
41116158
NACRES:
NA.32
species reactivity
human, mouse, rat
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable
enzyme immunoassay: suitable
input
sample type serum
sample type plasma
sample type culture supernatant(s)
sample type cell lysate
assay range
inter-assay cv: <15%
intra-assay cv: <10%
sensitivity: 9.92 pg/mL
standard curve range: 0.1–1000 pg/mL
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... GAST(2520)
General description
The Gastrin-I Enzyme Immunoassay (EIA) Kit is an in vitro quantitative assay for detecting Gastrin-I peptide based on the principle of Competitive Enzyme Immunoassay.
Gastrin is a peptide hormone released in gastrointestinal region of the body. It is specifically produced by the G-cells in stomach and duodenum. During embryogenesis, gastrin secretion is observed only in the pancreas. Gastrin is also localized to the renal tubules. The GAST gene is mapped to human chromosome 17q21.2.
Gastrin is a peptide hormone released in gastrointestinal region of the body. It is specifically produced by the G-cells in stomach and duodenum. During embryogenesis, gastrin secretion is observed only in the pancreas. Gastrin is also localized to the renal tubules. The GAST gene is mapped to human chromosome 17q21.2.
Immunogen
Gastrin, synthetic peptide
Application
For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Gastrin EIA Kit has been used to estimate the levels of gastrin hormone in plasma or serum sample.
Biochem/physiol Actions
Gastrin is responsible for epithelial cell proliferation and differentiation. Gastrin regulates the action of parietal cells in secretion of gastric acid and growth factors essential for stomach maintenance. Gastrin maintains sodium ion homeostasis and controls body′s blood pressure. Hypoxial conditions in in vitro and in vivo analysis may elevate the expression of gastrin hormone in cancer cells in order to promote angiogenesis.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Met. Corr. 1
Storage Class Code
8A - Combustible corrosive hazardous materials
Regulatory Information
常规特殊物品
低风险生物材料
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Metabolic Control by Inflammation and Immunity: Gastrin stimulates renal dopamine production by increasing the renal tubular uptake of l-DOPA.
Jiang X, et al.
American Journal of Physiology. Endocrinology and Metabolism, 312(1), E1-E1 (2017)
The gastrin-releasing peptide analog bombesin preserves exocrine and endocrine pancreas morphology and function during parenteral nutrition.
Pierre J F, et al.
American Journal of Physiology: Gastrointestinal and Liver Physiology, 309(6), G431-G442 (2015)
Pancreatic beta cells express the fetal islet hormone gastrin in rodent and human diabetes.
Dahan T, et al.
Diabetes (2016)
Increased gastrin gene expression provides a physiological advantage to mice under hypoxic conditions.
Laval M, et al.
American Journal of Physiology: Gastrointestinal and Liver Physiology, 308(2), G76-G84 (2014)
Genomic analysis reveals the molecular heterogeneity of ovarian clear cell carcinomas.
Tan D S, et al.
Clinical Cancer Research, 17(6), 1521-1534 (2011)
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Instructions
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