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Merck
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RAB0306

Human IL-6 ELISA Kit

for serum, plasma, cell culture supernatant and urine

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About This Item

NACRES:
NA.32
UNSPSC Code:
41116158

Key Documents

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Product Name

Human IL-6 ELISA Kit, for serum, plasma, cell culture supernatant and urine

species reactivity

human

packaging

kit of 96 wells (12 strips x 8 wells)

technique(s)

ELISA: suitable
capture ELISA: suitable

input

sample type urine
sample type cell culture supernatant(s)
sample type plasma
sample type serum

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 3 pg/mL
standard curve range: 1.37-1000 pg/mL

detection method

colorimetric

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... IL6(3569)

Application

Human IL-6 ELISA kit has been used for determining the levels of IL-6 in biological samples.
For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Biochem/physiol Actions

IL-6 (interleukin 6) is a pleiotropic cytokine that plays an important role in host defense by regulating immune and inflammatory responses. Produced by T cells, monocytes, fibroblasts, endothelial cells and keratinocytes, IL-6 has diverse biological functions. It stimulates B-cell differentiation and antibody production, synergizes with IL-3 in megakaryocyte development and platelet production, induces expression of hepatic acute-phase proteins, and regulates bone metabolism. IL-6 is associated with various autoimmune and inflammatory diseases. High levels of IL-6 are present in the synovial fluid from rheumatoid arthritis patients. It is also linked with chronic inflammatory proliferative disease and B cell malignancy, Castleman′s disease, and plasmacytoma/multiple myeloma.

Disclaimer

For research use only. Not for use in diagnostic procedures.

General description

The Human IL-6 ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human IL-6 in serum, plasma, cell culture supernatants and urine.

Immunogen

Recombinant Human I-L6

Other Notes

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

pictograms

Corrosion
GHS05

signalword

Warning

hcodes

H290

Hazard Classifications

Met. Corr. 1

Storage Class

8A - Combustible corrosive hazardous materials

Regulatory Information

常规特殊物品
含少量动物源组分生物产品
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Certificates of Analysis (COA)

Lot/Batch Number
0804B0140
1027J0140
0929J0140
0728J0140
0420J0140

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Apelin attenuates oxidative stress in human adipocytes.
Than A
The Journal of Biological Chemistry, 289(6), 3763-3774 (2014)
Interleukin-6: discovery of a pleiotropic cytokine.
Kishimoto T
Arthritis Research & Therapy, 8, S2-S2 (2006)
Genquan Yin et al.
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