RAB0539
Human AHSG / Alpha-2-HS-glycoprotein ELISA Kit
for serum, plasma and cell culture supernatants
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About This Item
NACRES:
NA.32
UNSPSC Code:
41116158
Product Name
Human AHSG / Alpha-2-HS-glycoprotein ELISA Kit, for serum, plasma and cell culture supernatants
species reactivity
human
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable
input
sample type plasma
sample type serum
sample type cell culture supernatant(s)
assay range
inter-assay cv: <10%
intra-assay cv: <12%
sensitivity: 0.2 ng/mL
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... AHSG(197)
Application
For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Biochem/physiol Actions
α 2-HS glycoprotein (AHSG), also referred to as fetuin-A, is a major serum protein component that exerts various calcium-dependent physiological activities and can mediate growth signaling in certain tumor cells. It can also act as a natural antagonist against specific TGF-β (transforming growth factor β) and BMP (bone morphogenetic protein) signaling proteins. High levels of fetuin-A in the serum is associated with mild osteogenesis imperfecta. On the other hand, reduced levels are seen in Paget′s disease. It is predicted as a potential biomarker for the early diagnosis of hypopharyngeal squamous cell carcinoma.
General description
This ELISA antibody pair detects human Alpha-2-HS-glycoprotein.
Other Notes
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
signalword
Warning
hcodes
pcodes
Hazard Classifications
Met. Corr. 1
Storage Class
8A - Combustible corrosive hazardous materials
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Proteomic identification of alpha-2-HS-glycoprotein as a plasma biomarker of hypopharyngeal squamous cell carcinoma.
Tian WD, et al.
International Journal of Clinical and Experimental Pathology, 8(8), 9021-9021 (2015)
Claas Jasper Steffen et al.
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In the elderly, osteoporotic fractures of the femur are associated with high morbidity and mortality. At the time of hospitalization and during pre-operative care identification of patients at risk for poor outcome despite an otherwise good clinical condition is challenging.
Association of alpha2-HS glycoprotein (AHSG, fetuin-A) polymorphism with AHSG and phosphate serum levels.
Osawa M, et al.
Human Genetics, 116(3), 146-151 (2005)
Margarida Sarmento-Dias et al.
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Instructions
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