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About This Item
NACRES:
NA.32
UNSPSC Code:
41116158
Gene information:
human ... LGALS3(3958)
Input:
sample type cell culture supernatant(s)
sample type serum
sample type plasma
sample type serum
sample type plasma
Species reactivity:
human
Storage temp.:
−20°C
Shipped in:
wet ice
species reactivity
human
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable
input
sample type cell culture supernatant(s)
sample type serum
sample type plasma
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 0.6 ng/mL
standard curve range: 0.819-200 ng/mL
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... LGALS3(3958)
General description
The LGALS3 enzyme-linked immunosorbent assay (ELISA) kit provides for the quantitative measurement of galectin-3 in cell culture supernatants, plasma, and serum. Galectin-3 belongs to the β-galactoside-binding protein family. It is an intracellular and extracellular lectin. Galectin-3 is expressed in immune cells and epithelial cells. It interacts with intracellular glycoproteins and plays a role in several biological processes such as angiogenesis, apoptosis, cell growth, adhesion, and differentiation.
Application
For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Other Notes
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
signalword
Warning
hcodes
pcodes
Hazard Classifications
Met. Corr. 1
Storage Class
8A - Combustible corrosive hazardous materials
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
低风险生物材料
常规特殊物品
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Yukinori Takenaka et al.
Glycoconjugate journal, 19(7-9), 543-549 (2004-02-06)
Galectin-3, a 31 kDa member of the beta-galactoside-binding proteins, is an intracellular and extracellular lectin which interacts with intracellular glycoproteins, cell surface molecules and extracellular matrix proteins. Galectin-3 is expressed widely in epithelial and immune cells and its expression is
Shizhan Ma et al.
Journal of diabetes investigation, 11(5), 1295-1302 (2020-03-21)
Galectin-3 (Gal3) contributes to insulin resistance, inflammation and obesity, the three risk factors for mild cognitive impairment (MCI) in type 2 diabetes mellitus patients. A total of 134 hospitalized type 2 diabetes mellitus patients were assessed by the Montreal Cognitive Assessment method
Alexander E Berezin et al.
Biomarkers in medicine, 13(9), 737-750 (2019-06-04)
Aim: to evaluate the associations between signatures of apoptotic endothelial cell-derived microvesicles (MVs) with phenotypes of chronic heart failure (HF). Methods: The study cohort consisted of 388 prospectively involved subjects with HF patients with predominantly reduced left ventricular ejection fraction
Katarzyna Mackowiak-Lewandowicz et al.
Pediatric nephrology (Berlin, Germany) (2022-02-26)
Glomerular hyperfiltration, initiating development of obesity-related glomerulopathy, results in an enlargement of the glomeruli and unsealing of the filtration barrier. It can be followed by adaptive focal segmental glomerulosclerosis and chronic kidney disease (CKD). The aim of the study was
Prasoon Verma et al.
Pediatric research, 85(4), 527-532 (2019-01-27)
Invasive candidiasis is an important cause of fungal infections in immunocompromised patients, including premature infants. The S-type lectin, galectin-3 (gal3), is increasingly recognized for its role in antifungal host defense. This study tested the hypothesis that tissue gal3 expression is
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