Merck
CN
All Photos(3)

Documents

S006

Sigma-Aldrich

Ketanserin (+)-tartrate salt

≥97%, solid

Sign Into View Organizational & Contract Pricing

Synonym(s):
3-(2-[4-(4-Fluorobenzoyl)-1-piperidinyl]ethyl)-2,4(1H,3H)-quinazolinedione (+)-tartrate salt, R 41468 (+)-tartrate salt
Empirical Formula (Hill Notation):
C22H22FN3O3 · C4H6O6
CAS Number:
Molecular Weight:
545.51
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.77

Quality Level

Assay

≥97%

form

solid

color

white

solubility

ethanol: 3 mg/mL
DMSO: 52 mg/mL (lit.)(lit.)
0.1 M HCl: 6 mg/mL (lit.)(lit.)

storage temp.

2-8°C

SMILES string

O[C@H]([C@@H](O)C(O)=O)C(O)=O.Fc1ccc(cc1)C(=O)C2CCN(CC2)CCN3C(=O)Nc4ccccc4C3=O

InChI

1S/C22H22FN3O3.C4H6O6/c23-17-7-5-15(6-8-17)20(27)16-9-11-25(12-10-16)13-14-26-21(28)18-3-1-2-4-19(18)24-22(26)29;5-1(3(7)8)2(6)4(9)10/h1-8,16H,9-14H2,(H,24,29);1-2,5-6H,(H,7,8)(H,9,10)/t;1-,2-/m.1/s1

InChI key

KMTLTEVOQLMYRS-LREBCSMRSA-N

Gene Information

Looking for similar products? Visit Product Comparison Guide

Application

Ketanserin (+)-tartrate salt has been used:
  • as a 5HT2A antagonist in Krebs-Henseleit buffer solution
  • for hormonal treatment to study the effects of exogenous manipulation of different hormonal systems in interaction with parasite infection on client′s behavior
  • to study the behavioural changes of incision pain rats

Biochem/physiol Actions

Ketanserin stimulates collagen synthesis and is involved in wound healing.
Selective 5-HT2 serotonin receptor antagonist. Ketanserin significantly reduces nicotine self-administration in rats, supporting an unexpected involvement of serotonin in nicotine addiction.

Pictograms

Skull and crossbones

Signal Word

Danger

Hazard Statements

Precautionary Statements

Hazard Classifications

Acute Tox. 3 Oral

Storage Class Code

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Documents related to the products that you have purchased in the past have been gathered in the Document Library for your convenience.

Visit the Document Library

Difficulty Finding Your Product Or Lot/Batch Number?

Product numbers are combined with Pack Sizes/Quantity when displayed on the website (example: T1503-25G). Please make sure you enter ONLY the product number in the Product Number field (example: T1503).

Example:

T1503
Product Number
-
25G
Pack Size/Quantity

Additional examples:

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

enter as 1.000309185)

Having trouble? Feel free to contact Technical Service for assistance.

Lot and Batch Numbers can be found on a product's label following the words 'Lot' or 'Batch'.

Aldrich Products

  • For a lot number such as TO09019TO, enter it as 09019TO (without the first two letters 'TO').

  • For a lot number with a filling-code such as 05427ES-021, enter it as 05427ES (without the filling-code '-021').

  • For a lot number with a filling-code such as STBB0728K9, enter it as STBB0728 without the filling-code 'K9'.

Not Finding What You Are Looking For?

In some cases, a COA may not be available online. If your search was unable to find the COA you can request one.

Request COA

Effects of short-term exposure to ectoparasites on fish cortisol and hematocrit levels
Triki Z, et al.
Marine biology, 163(9), 187-187 (2016)
Ketanserin in wound healing and fibrosis: investigations into its mechanism of action
Serotonin, 12(6), 451-455 (1990)
The 5-HT2A receptor potassium-chloride cotransporter 2 signaling pathway in a rat incision pain model
Dong R, et al.
Experimental and Therapeutic Medicine, 12(6), 3583-3588 (2016)
Iris Lim et al.
European journal of pharmacology, 818, 328-334 (2017-11-07)
Isolated ureteral strips develop spontaneous phasic contractile activity which is enhanced by 5-hydroytryptamine (5-HT). The aim of this study was to identify the receptor subtype mediating these responses and to determine whether responses to 5-HT change with age. The frequency
Antagonism of lateral saphenous vein serotonin receptors from steers grazing endophyte-free, wild-type, or novel endophyte-infected tall fescue
Klotz JL, et al.
Journal of Animal Science, 91(9), 4492-4500 (2013)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service