S0170
neo-Saxitoxin
solution
Synonym(s):
neo-STX
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About This Item
Empirical Formula (Hill Notation):
C10H17N7O5
CAS Number:
Molecular Weight:
315.29
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
form
solution
shipped in
dry ice
storage temp.
−20°C
SMILES string
NC(=O)OC[C@H]1[C@@H]2N=C(N)N[C@]23N(CCC3(O)O)C(=N)N1O
Biochem/physiol Actions
Sodium channel blocker; differs structurally from saxitoxin in that the hydrogen on N-1 is replaced by a hydroxyl group leading to pH dependent differences between the two toxins.
Physical form
Solution in 0.03 N acetic acid, pH 3
Other Notes
Isolated originally from dinoflagellate
One of a group of neurotoxins produced by the organism responsible for "red tides".
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Hu, S.L., and Kao, C.Y.,
The Journal of General Physiology, 97, 97-578 (1991)
Yieytes, M.R. et al.
Analytical Biochemistry, 221, 87-87 (1993)
Wichmann, C.F., et al.
Tetrahedron Letters, 22, 1941-1941 (1981)
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