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About This Item
Linear Formula:
Na2[Fe(CN)5NO] · 2H2O
CAS Number:
Molecular Weight:
297.95
EC Number:
238-373-9
UNSPSC Code:
12352300
MDL number:
SMILES string
O.O.[Na+].[Na+].O=N[Fe--](C#N)(C#N)(C#N)(C#N)C#N
InChI
1S/5CN.Fe.NO.2Na.2H2O/c5*1-2;;1-2;;;;/h;;;;;;;;;2*1H2/q;;;;;2*-1;2*+1;;
InChI key
OIRZWVYIQXBRFC-UHFFFAOYSA-N
Biochem/physiol Actions
Releases NO in vivo, thus activating guanylyl cyclase, ADP-ribosyltransferase, and cyclooxygenase and inhibiting lipoxygenase. Induces vasodilation and inhibits platelet aggregation.
Other Notes
This product has been replaced by 228710-Sigma-Aldrich | Sodium nitroferricyanide(III) dihydrate, ACS reagent, 99% | Na2[Fe(CN)5NO]
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signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral
Storage Class
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
Regulatory Information
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Related Content
Feelisch, M.
Journal of Cardiovascular Pharmacology, 17, S25-S25 (1991)
B Brüne et al.
The Journal of biological chemistry, 264(15), 8455-8458 (1989-05-25)
Sodium nitroprusside is a vasodilator and an inhibitor of platelet activation. It is thought that these effects are mediated by the spontaneous release of nitric oxide and stimulation of cytosolic guanylate cyclase. We have found that sodium nitroprusside (5-200 microM)
D Salvemini et al.
The Journal of clinical investigation, 97(11), 2562-2568 (1996-06-01)
We have evaluated the contributions of nitric oxide (NO) and prostacyclin (PGI2) in the in vivo antiplatelet effects of clinically useful nitrovasodilators. In rats, intravenous infusion of three NO donors, glyceryl trinitrate, sodium nitroprusside, or 3'-morpholinosydnonimine, the stable metabolite of
