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About This Item
Linear Formula:
HOC6H4CH(CH2NHCH3)OH
CAS Number:
Molecular Weight:
167.21
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
202-300-9
MDL number:
Assay:
≥98%
assay
≥98%
mp
187 °C (dec.) (lit.)
storage temp.
2-8°C
SMILES string
OC1=CC=C(C(O)CNC)C=C1
InChI
1S/C9H13NO2/c1-10-6-9(12)7-2-4-8(11)5-3-7/h2-5,9-12H,6H2,1H3
InChI key
YRCWQPVGYLYSOX-UHFFFAOYSA-N
Gene Information
human ... ADRA1A(148), ADRA1B(147), ADRA1D(146), ADRA2A(150), ADRA2B(151), ADRA2C(152)
Application
(±)-Synephrine has been used as an alkaloid to investigate its in vitro antiviral, antibacterial, antifungal and cytotoxicity activities.
Biochem/physiol Actions
Synephrine is naturally found in citrus plants belonging to the Rutaceae family. It is a sympathomimetic alkaloid. Synephrine has 3 isomeric forms, such as m-synephrine, p-synephrine and o-synephrine. It exhibits β-adrenergic properties.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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Claudio Medana et al.
Analytical and bioanalytical chemistry, 405(2-3), 1105-1113 (2012-12-05)
The occurrence of some cases of positive results in anti-doping analysis of octopamine requires clarification as to whether its methylated derivative synephrine could be a metabolic precursor of octopamine itself. Synephrine is a natural phenylethylamine derivative present in some food
C M Brown et al.
British journal of pharmacology, 93(2), 417-429 (1988-02-01)
1. The activities of the (-)- and (+)-forms of m- and p-octopamine and m- and p-synephrine on alpha 1-adrenoceptors from rat aorta and anococcygeus and alpha 2-adrenoceptors from rabbit saphenous vein were compared with those of noradrenaline (NA). 2. The
Shun-ichi Ishiuchi et al.
The journal of physical chemistry. A, 115(37), 10363-10369 (2011-08-09)
In our previous work, we found that synephrine has six conformers in the gas phase, while adrenaline, which is a catecholamine and has the same side chain as synephrine, has been reported to have only two conformers. To determine the
Global Trade Item Number
| SKU | GTIN |
|---|---|
| S0752-10G | 04061832273921 |
| S0752-25G | 04061832286594 |
| S0752-5G | 04061836830687 |
| S0752-100G | 04061832286587 |
