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S0755

Dimethyl succinate

Name: Dimethyl succinate
Brand: SIGMA

Synonym(s):

Succinic acid dimethyl ester

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About This Item

Linear Formula:

CH₃OCOCH₂CH₂COOCH₃

CAS Number:

106-65-0

Molecular Weight:

146.14

EC Number:

203-419-9

UNSPSC Code:

12352100

MDL number:

MFCD00008466

Beilstein/REAXYS Number:

956776

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Properties

vapor pressure

0.3 mmHg ( 20 °C)

autoignition temp.

689 °F

expl. lim.

8.5 %

refractive index

n20/D 1.419 (lit.)

bp

200 °C (lit.)

mp

16-19 °C (lit.)

density

1.117 g/mL at 25 °C (lit.)

SMILES string

COC(=O)CCC(=O)OC

InChI

1S/C6H10O4/c1-9-5(7)3-4-6(8)10-2/h3-4H2,1-2H3

InChI key

MUXOBHXGJLMRAB-UHFFFAOYSA-N

Description

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pictograms

GHS07

signalword

Warning

hcodes

H319

pcodes

P264 - P280 - P305 + P351 + P338 - P337 + P313

Hazard Classifications

Eye Irrit. 2

Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

201.2 °F - closed cup

flash_point_c

94 °C - closed cup

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

Regulatory Information

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Synthesis and activity of N-oxalylglycine and its derivatives as Jumonji C-domain-containing histone lysine demethylase inhibitors.

Shohei Hamada et al.

Bioorganic & medicinal chemistry letters, 19(10), 2852-2855 (2009-04-11)

N-Oxalylglycine (NOG) derivatives were synthesized, and their inhibitory effect on histone lysine demethylase activity was evaluated. NOG and compound 1 inhibited histone lysine demethylases JMJD2A, 2C and 2D in enzyme assays, and their dimethyl ester prodrugs DMOG and 21 exerted