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Merck
CN

S102

Sigma-Aldrich

S-(−)-SKF-38393 hydrochloride

solid

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About This Item

Empirical Formula (Hill Notation):
C16H17NO2 · HCl
CAS Number:
81702-43-4
Molecular Weight:
291.77
MDL number:
MFCD00069365
UNSPSC Code:
12352202
PubChem Substance ID:
24899459
NACRES:
NA.77

Key Documents

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form

solid

optical activity

[α]27/D −14.8°, c = 1.7 in methanol(lit.)

color

tan

SMILES string

Cl.Oc1cc2CCNC[C@@H](c3ccccc3)c2cc1O

InChI

1S/C16H17NO2.ClH/c18-15-8-12-6-7-17-10-14(13(12)9-16(15)19)11-4-2-1-3-5-11;/h1-5,8-9,14,17-19H,6-7,10H2;1H/t14-;/m0./s1

InChI key

YEWHJCLOUYPAOH-UQKRIMTDSA-N

Biochem/physiol Actions

D1 dopamine receptor agonist; less active enantiomer of (±)-SKF-38393.

Disclaimer

Photosensitive

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Gnana P Krishnamoorthy et al.
Cancer discovery, 9(2), 264-281 (2018-10-12)
Translation initiation is orchestrated by the cap binding and 43S preinitiation complexes (PIC). Eukaryotic initiation factor 1A (EIF1A) is essential for recruitment of the ternary complex and for assembling the 43S PIC. Recurrent EIF1AX mutations in papillary thyroid cancers are

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