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Merck
CN

S1064

Sigma-Aldrich

Monoclonal Anti-SERCa1 ATPase antibody produced in mouse

clone IIH11, ascites fluid

Synonym(s):

Anti-Sarcoplasmic or Endoplasmic Reticulum Ca2+ ATPase1

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About This Item

MDL number:
UNSPSC Code:
12352203
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biological source

mouse

conjugate

unconjugated

antibody form

ascites fluid

antibody product type

primary antibodies

clone

IIH11, monoclonal

contains

0.05% sodium azide

species reactivity

rat, rabbit, canine, guinea pig, mouse

should not react with

human

technique(s)

indirect immunofluorescence: suitable
western blot: suitable

isotype

IgG1

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

Gene Information

mouse ... Atp2a1(11937)
rat ... Atp2a1(116601)

Immunogen

purified rabbit skeletal muscle sarcoplasmic reticulum.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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A O Jorgensen et al.
Cell motility and the cytoskeleton, 9(2), 164-174 (1988-01-01)
Ca2+-ATPase of the sarcoplasmic reticulum was localized in cryostat sections from three different adult canine skeletal muscles (gracilis, extensor carpi radialis, and superficial digitalis flexor) by immunofluorescence labeling with monoclonal antibodies to the Ca2+-ATPase. Type I (slow) myofibers were strongly
S Feske et al.
Journal of immunology (Baltimore, Md. : 1950), 165(1), 297-305 (2000-06-22)
The expression of cytokine genes and other inducible genes is crucially dependent on the pattern and duration of signal transduction events that activate transcription factor binding to DNA. Two infant patients with SCID and a severe defect in T cell
Jens H Westhoff et al.
Cell calcium, 34(3), 261-269 (2003-07-31)
Cellular signaling proteins such as metabotropic glutamate receptors, Shank, and different types of ion channels are physically linked by Vesl (VASP/Ena-related gene up-regulated during seizure and LTP)/Homer proteins [Curr. Opin. Neurobiol. 10 (2000) 370; Trends Neurosci. 23 (2000) 80; J.
Yolanda Gutiérrez-Martín et al.
European journal of biochemistry, 271(13), 2647-2657 (2004-06-23)
The Ca(2+)-ATPase of skeletal muscle sarcoplasmic reticulum (SERCA), an integral membrane protein, becomes irreversibly inactivated in vitro by the addition of a single bolus of peroxynitrite with a K(0.5) of 200-300 microm, and this results in a large decrease of

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