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Merck
CN

S1561

Sigma-Aldrich

Anti-Serotonin 5-HT3 Receptor antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

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About This Item

MDL number:
UNSPSC Code:
12352203
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biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

clone

polyclonal

form

buffered aqueous solution

species reactivity

mouse, rat

technique(s)

immunohistochemistry (frozen sections): 2-5 μg/mL using 4% paraformaldehyde-fixed, frozen mouse or rat brain tissues

shipped in

wet ice

storage temp.

2-8°C

Gene Information

mouse ... Htr3a(15561)
rat ... Htr3a(79246)

Immunogen

synthetic peptide (SLEKRDEMREVARD) corresponding to amino acids 444-457 of rat serotonin 5-HT3 receptor protein, conjugated to KLH. This sequence contains one amino acid substitution with the mouse sequence and two amino acid substitutions with the human sequence.

Biochem/physiol Actions

Not recommended for immunoblotting of whole brain extracts

Physical form

Solution in 0.05 M sodium phosphate buffer, pH 7.5, containing 0.2% gelatin and 0.1% sodium azide

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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H Nguyen et al.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, 20(3), 228-235 (2007-10-09)
The serotonin neurotransmitter system, including the 5-HT(3) receptor, has been implicated in the genesis of fatigue in patients with liver disease. Therefore, we examined the possible role of 5-HT(3) receptors in cholestasis-associated fatigue. Rats were either bile duct resected (BDR)
R C C Poon et al.
Environmental research, 105(2), 200-211 (2007-02-13)
Actual risk and risk management of exposure to ionizing radiation are among the most controversial areas in environmental health protection. Recent developments in radiobiology especially characterization of bystander effects have called into question established dogmas and are thought to cast
C Mazzia et al.
Neuroscience, 116(4), 1033-1041 (2003-03-06)
The presence of 5-hydroxytryptamine(3) receptors on enteric neurons is known from pharmacological data that date back more than 40 years. However, an adequate account of which neurons bear these receptors has not been made because suitable antisera have not been

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