S1634
L-Saccharopine
Synonym(s):
ε-N-(L-glutar-2-yl)-L-lysine, N6-(L-1,3-dicarboxylpropyl)-L-lysine
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About This Item
Empirical Formula (Hill Notation):
C11H20N2O6
CAS Number:
Molecular Weight:
276.29
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
assay
≥98%
form
powder
color
white
storage temp.
−20°C
SMILES string
N[C@@H](CCCCN[C@@H](CCC(O)=O)C(O)=O)C(O)=O
InChI
1S/C11H20N2O6/c12-7(10(16)17)3-1-2-6-13-8(11(18)19)4-5-9(14)15/h7-8,13H,1-6,12H2,(H,14,15)(H,16,17)(H,18,19)/t7-,8-/m0/s1
InChI key
ZDGJAHTZVHVLOT-YUMQZZPRSA-N
Preparation Note
Prepared enzymatically
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Storage Class
11 - Combustible Solids
Regulatory Information
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J Dancis et al.
American journal of human genetics, 31(3), 290-299 (1979-05-01)
Enzyme assays of skin fibroblasts from five children with familial hyperlysinemia from unrelated families are added to the previous report of three children from two unrelated families. In all instances there was a deficiency in lysine-ketoglutarate reductase, saccharopine dehydrogenase, and
G Tang et al.
The Plant journal : for cell and molecular biology, 23(2), 195-203 (2000-08-06)
Both plants and animals catabolize lysine via saccharopine by two consecutive enzymes, lysine-ketoglutarate reductase (LKR) and saccharopine dehydrogenase (SDH), which are linked on a single polypeptide. We recently demonstrated that Arabidopsis plants possess not only a bifunctional LKR/SDH but in
C Esmahan et al.
Applied and environmental microbiology, 60(6), 1705-1710 (1994-06-01)
Penicillium chrysogenum L2, a lysine auxotroph blocked in the early steps of the lysine pathway before 2-aminoadipic acid, was able to synthesize penicillin when supplemented with lysine. The amount of penicillin produced increased as the level of lysine in the
V V Rao et al.
Comparative biochemistry and physiology. B, Comparative biochemistry, 103(1), 221-224 (1992-09-01)
1. Developmental aspects of L-lysine-ketoglutarate reductase, the first enzyme in saccharopine pathway of L-lysine degradation in rat liver and brain tissues were studied. 2. Although the adult rat brain shows negligible activity, the enzyme activity was shown to be highly
Valeria Fochi et al.
The New phytologist, 213(1), 365-379 (2016-11-20)
Orchids are highly dependent on their mycorrhizal fungal partners for nutrient supply, especially during early developmental stages. In addition to organic carbon, nitrogen (N) is probably a major nutrient transferred to the plant because orchid tissues are highly N-enriched. We
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