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Merck
CN

S1640

Sigma-Aldrich

Anti-Secretory Component (IgA) (Bound and Free) antibody produced in goat

whole antiserum

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About This Item

MDL number:
UNSPSC Code:
12352203
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biological source

goat

conjugate

unconjugated

antibody form

whole antiserum

antibody product type

primary antibodies

clone

polyclonal

contains

15 mM sodium azide

species reactivity

human

technique(s)

indirect ELISA: 1:5,000
quantitative precipitin assay: 1.6-2.4 mg/mL

shipped in

dry ice

storage temp.

−20°C

Immunogen

secretory component from human IgA.

Application

Anti-Secretory Component (IgA) (Bound and Free) antibody produced in goat was used in immunoblotting of Pneumococcal protein extracts.

Biochem/physiol Actions

IgA antibody is secretory antibody and is present abundantly in mucous linings of gastrointestinal, respiratory and genitourinary tracts, tears, colostrum and saliva. Thus secretory IgA contributes to the humoral defense mechanism against the pathogens on mucosal surfaces.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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N Schuster-Woldan et al.
Molecular human reproduction, 3(9), 743-747 (1997-11-14)
Gravidin is a potent phospholipase A2 inhibitor that may contribute to the maintenance of human pregnancy. The aims of this study were to determine firstly, the site of gravidin synthesis within placental membranes and secondly, whether the antiprogestin compound, RU486
Adriana T Moreno et al.
Clinical and vaccine immunology : CVI, 19(4), 499-507 (2012-02-18)
Pneumococcal surface protein C (PspC) is an important candidate for a cost-effective vaccine with broad coverage against pneumococcal diseases. Previous studies have shown that Streptococcus pneumoniae is able to bind to both human factor H (FH), an inhibitor of complement
Jan Holmgren et al.
Nature medicine, 11(4 Suppl), S45-S53 (2005-04-07)
There is currently great interest in developing mucosal vaccines against a variety of microbial pathogens. Mucosally induced tolerance also seems to be a promising form of immunomodulation for treating certain autoimmune diseases and allergies. Here we review the properties of

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