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Merck
CN

S3056

Sigma-Aldrich

Anti-SH-PTP2 (SHP-2) antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

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About This Item

MDL number:
UNSPSC Code:
12352203
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biological source

rabbit

conjugate

unconjugated

antibody form

IgG fraction of antiserum

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 70 kDa

species reactivity

human

technique(s)

microarray: suitable
western blot: 1:5,000 using human Jurkat cells cell extract

shipped in

dry ice

storage temp.

−20°C

Gene Information

human ... PTPN11(5781)

Immunogen

synthetic peptide corresponding to amino acids 573-593 of human SH-PTP2.

Biochem/physiol Actions

The sequence of the immunizing peptide is highly conserved in rat and mouse SH-PTP2 (single amino acid substitution).

Physical form

Solution in 0.01 M phosphate buffered saline pH 7.4, containing 15 mM sodium azide

Regulatory Information

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Akt inhibitor MK2206 prevents influenza pH1N1 virus infection in vitro.
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The hypoxic microenvironment of the bone marrow, known as the hypoxic niche, supports hematopoietic stem cell quiescence and maintains long-term repopulation activity. Hypoxia also affects the expansion of progenitor cells and enhances erythropoiesis and megakaryopoiesis. In contrast to the known
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Although alteration in host cellular translation machinery occurs in virus-infected cells, the role of such alteration and the precise pathogenic processes are not well understood. Influenza A virus (IAV) infection shuts off host cell gene expression at transcriptional and translational
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BMC cancer, 14, 442-442 (2014-06-17)
Tumor invasion and metastasis represent a major unsolved problem in cancer pathogenesis. Recent studies have indicated the involvement of Src-homology 2 domain-containing tyrosine phosphatase 2 (SHP2) in multiple malignancies; however, the role of SHP2 in oral cancer progression has yet
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PloS one, 9(11), e113634-e113634 (2014-11-21)
Dengue virus (DENV) represents a major threat to public health worldwide. Early DENV diagnosis should not only detect the infection but also identify patients with a higher likelihood to develop severe cases. Previous studies have suggested the potential for NS1

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