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Merck
CN

S4508

Sigma-Aldrich

[D-Trp8, D-Cys14]-Somatostatin

≥97% (HPLC)

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About This Item

Empirical Formula (Hill Notation):
C76H104N18O19S2
CAS Number:
Molecular Weight:
1637.88
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
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Assay

≥97% (HPLC)

storage temp.

−20°C

SMILES string

CC(N)C(=O)NCC(=O)NC1CSSCC(NC(=O)C(CO)NC(=O)C(NC(=O)C(Cc2ccccc2)NC(=O)C(NC(=O)C(CCCCN)NC(=O)C(Cc3c[nH]c4ccccc34)NC(=O)C(Cc5ccccc5)NC(=O)C(Cc6ccccc6)NC(=O)C(CC(N)=O)NC(=O)C(CCCCN)NC1=O)C(C)O)C(C)O)C(O)=O

Amino Acid Sequence

Ala-Gly-Cys-Lys-Asn-Phe-Phe-D-Trp-Lys-Thr-Phe-Thr-Ser-D-Cys [Disulfide Bridge: 3−14]

Biochem/physiol Actions

Potent somatostatin analog

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Brown, M., et al.
Science, 96, 1467-1467 (1977)
J C Reubi et al.
Endocrinology, 110(3), 1049-1051 (1982-03-01)
Saturable and high affinity binding sites have been obtained for an iodinated somatostatin-28 (SS-28) analog, [Leu8,D-Trp22,125I-Tyr25] SS-28, in a membrane preparation from hamster insulinoma, mainly composed of pancreatic beta-cells. Specific binding is maximal after 1 hour incubation at 22C and

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