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Merck
CN

S4751

Sigma-Aldrich

Stearic acid

Grade I, ≥98.5% (capillary GC)

Synonym(s):

1-Heptadecanecarboxylic acid, C18:0, Cetylacetic acid, NSC 25956, NSC 261168, Octadecanoic acid, Stearophanic acid

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About This Item

Linear Formula:
CH3(CH2)16COOH
CAS Number:
57-11-4
Molecular Weight:
284.48
Beilstein:
608585
EC Number:
200-313-4
MDL number:
MFCD00002752
UNSPSC Code:
12352106
PubChem Substance ID:
24899616
NACRES:
NA.25

Key Documents

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vapor pressure

1 mmHg ( 173.7 °C)

Quality Level

200

type

Grade I

Assay

≥98.5% (capillary GC)

form

powder

bp

361 °C (lit.)

mp

67-72 °C (lit.)

solubility

chloroform: 100 mg/mL, clear, colorless

density

0.845 g/cm3

functional group

carboxylic acid

lipid type

saturated FAs

shipped in

ambient

storage temp.

2-8°C

SMILES string

CCCCCCCCCCCCCCCCCC(O)=O

InChI

1S/C18H36O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h2-17H2,1H3,(H,19,20)

InChI key

QIQXTHQIDYTFRH-UHFFFAOYSA-N

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General description

Stearic acid is a C18 saturated fatty acid.

Application

Stearic acid has been used in fatty acid preparations.

Biochem/physiol Actions

β-Oxidation of stearic acid yields eight FADH2 (flavin adenine dinucleotide) and NADH2 (nicotinamide adenine dinucleotide) molecules and nine acetyl-CoA molecules.

Storage Class Code

11 - Combustible Solids

WGK

nwg

Flash Point(F)

392.0 °F - Cleveland open cup

Flash Point(C)

200 °C - Cleveland open cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
0000505997
0000505997
0000485028
0000485030
0000485030

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Hypoxia potentiates palmitate-induced pro-inflammatory activation of primary human macrophages
Snodgrass Ryan G, et al.
The Journal of Biological Chemistry, 291(1), 413-424 (2016)
Solid liquid phase diagrams of binary fatty acid mixtures?Palmitic/stearic with oleic/linoleic/linolenic acid mixture
Eckert Karl-Andreas, et al.
Thermochimica Acta, 630, 50-63 (2016)
Sports Nutrition (1999)
Construction and comparison of solid liquid phase diagrams of binary sat-sat and unsat-unsat fatty acid mixtures comprising two of palmitic/stearic/oleic/linoleic/linolenic acid
Eckert KA, et al.
Journal of Environmental Research And Development, 10(4), 1-1 (2016)
Hua Ning et al.
Nutrients, 8(4), 227-227 (2016-04-23)
The detrimental role of hepatic lipotoxicity has been well-implicated in the pathogenesis of NAFLD. Previously, we reported that inhibiting autophagy aggravated saturated fatty acid (SFA)-induced hepatotoxicity. Insulin, a physiological inhibitor of autophagy, is commonly increased within NAFLD mainly caused by
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Stearic Acid in Cell Culture

Supplement cell culture systems with fatty acids for biomanufacturing heterologous proteins like monoclonal antibodies.

脂质诱导的胰岛素耐受性

脂肪组织中的胰岛素耐受性减少了循环游离脂肪酸的摄入，并增加了脂肪酶对储存甘油三酯的水解。了解与胰岛素耐受性相关的激素、细胞因子和脂肪因子。

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