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S5393

Sigma-Aldrich

Serum minus IgA/IgM/IgG human

lyophilized powder

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NACRES:
NA.46

biological source

human

Quality Level

300

conjugate

unconjugated

form

lyophilized powder

contains

15 mM sodium azide

packaging

vial of 0.5 mL

storage temp.

2-8°C

target post-translational modification

unmodified

Related Categories

General description

Serum is the liquid component of blood that includes proteins, immunoglobulin and electrolytes. The product can be used for selective removal of contaminating antibodies when immobilized on a solid matrix. This product can also be used in anti-protective antigen (anti-PA) IgG measurements using PA coupled microspheres. Human serum deficient of IgG, IgA, and IgM can react specifically with anti-human whole serum but does not show reactivity with anti-human IgG, IgA, or IgM.

Application

Serum minus IgA/IgM/IgG human has been used as a control serum in immunoelectrophoresis, immunodiffusion,enzyme linked immunosorbent assay. It has also been used as
  • control sera to assess neuraminidase inhibition
  • microneutralization assay
  • single radial hemolysis (SRH) repeatability assay

Quantity

Each vial contains at least 25 mg protein

Reconstitution

Reconstitute with 0.5 mL deionized water.

Disclaimer

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

高风险级别生物产品--人源产品

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R E Biagini et al.
Occupational and environmental medicine, 61(8), 703-708 (2004-07-20)
To evaluate potential exposure to Bacillis anthracis (Ba) spores in sampling/decontamination workers in the aftermath of an anthrax terror attack. Fifty six serum samples were obtained from workers involved in environmental sampling for Ba spores at the American Media, Inc.
Karina Jawinski et al.
Frontiers in immunology, 10, 2661-2661 (2019-12-05)
Current influenza vaccines manufactured using eggs have considerable limitations, both in terms of scale up production and the potential impact passaging through eggs can have on the antigenicity of the vaccine virus strains. Alternative methods of manufacture are required, particularly
Thorunn A Olafsdottir et al.
Frontiers in immunology, 8, 1872-1872 (2018-01-24)
Influenza vaccination remains the best strategy for the prevention of influenza virus-related disease and reduction of disease severity and mortality. However, there is large individual variation in influenza vaccine responses. In this study, we investigated the effects of gender, age
Fabrizio Biuso et al.
Influenza and other respiratory viruses, 13(5), 504-516 (2019-08-15)
Formulation of neuraminidase (NA) within influenza vaccines is gaining importance in light of recent human studies. The enzyme-linked lectin assay (ELLA) is considered a reliable assay to evaluate human anti-NA antibodies. To overcome interference by hemagglutinin (HA)-specific antibodies and detect
Method for Simultaneous Measurement of Antibodies to 23 Pneumococcal Capsular Polysaccharides
Raymond E. Biagini, Sonela A. Schlottmann
Clinical and Vaccine Immunology : CVI, 10(5), 744-750 (2003)
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